Protein Alignment CG5916 and TBC1D26

DIOPT Version :10

• Sequence 1: NP_650524.1
• Gene: CG5916 / 41960
• FlyBaseID: FBgn0038401
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_001375394.1
• Gene: TBC1D26 / 353149
• HGNCID: 28745
• Length: 468
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 66/283 - (23%)
• Similarity: 117/283 - (41%)
• Gaps: 54/283 - (19%)

  Fly    40 TRRRMKWEAILQQNTDLTQVDA--KLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLR 102
            ::|..||:.:|   .|.|:..:  ||.:.:.|.||...|...|..:......:.::|..::.:..
Human    72 SKRTNKWQKML---ADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKE 133

  Fly   103 TEPFDKEISDSISIDLPRTFPDNI----HFDMKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLL 163
            .......|...|.:|:..|...::    .|.:|:|.|.:||:||:.:|.:|||.:.|:.|..:||
Human   134 KGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAILL 198

  Fly   164 IVTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIA 228
            :.. .||.:||.|    ..::..::|.|.|.|.|.|:...:::.:..|.:.||:...||
Human   199 LCL-PEEDAFWAL----TQLLAVFYSPNTAWLERLLSHQEQVLHKSFPKIMRHLGKEGL------ 252

  Fly   229 SKWFICI-----------FAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAIL------ 276
                 ||           |.:.......||:||....||.:::.......|..|:..::
Human   253 -----CIEGSMLTRLLRCFLDGKSFGLTLRLWDVFILEGARVLTAMVHASFKIHRKHLMKLSWST 312

  Fly   277 ------------GCDDIAALANL 287
                        ..:|.|.|.||
Human   313 VWEFQERLSQSWALEDNAVLRNL 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_650524.1	TBC	67..276	CDD:214540	53/223 (24%)
TBC1D26	NP_001375394.1	TBC	98..306	CDD:214540	53/223 (24%)