DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and Tbc1d15-17

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	55/275 - (20%)
Similarity:	104/275 - (37%)	Gaps:	64/275 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 AKLKRYI-RKGIPGPYRPDVW-----------MKISGAAAAQRRSPDLFR------NLLRTEPFD 107
            |::|..| |.|:....||:||           ..:......:::|.:.:.      .:..|:..:
  Fly   362 ARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWLAMTTTQEAN 426

  Fly   108 ----KEISDSISIDLPRT--------FPDNIHFDMKKQRLYNILIAYAHHNRDVGYCQGLNYIAG 160
                :|....|..|:.||        ..||.:..:    |..||:.|..:|.|:||.||::.:..
  Fly   427 FCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTL----LQGILMTYVMYNFDLGYVQGMSDLLA 487

  Fly   161 LLLIVTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELV-IRRIPAVN----RHVDNL 220
            .:|.:..:|..:||.....:|.:...: ..:.|.:....|..|.|: ....|..|    ...||:
  Fly   488 PILEIQVNEVDTFWCFVGFMELVFTNF-DIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNM 551

  Fly   221 GLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAE----GYKIVFRAAL---------------T 266
                 ....:|.:..:...|..|.||::|:|::..    .:.::|..|:               |
  Fly   552 -----YFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFSVAILDQETRVIIDSQYEFT 611

  Fly   267 MFVTHKNAILGCDDI 281
            ..:.|.|.:.|..|:
  Fly   612 EILKHVNELSGNIDV 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	51/262 (19%)
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	47/238 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456565
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840