DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and Tbc1d9

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_006255308.1	Gene:	Tbc1d9 / 304645	RGDID:	1308221	Length:	1262	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	83/287 - (28%)
Similarity:	139/287 - (48%)	Gaps:	46/287 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LKTLTRRR----------------MKW--------EAILQQNTDLTQVDAKLKRYIRKGIPGPYR 76
            |.|:.|||                ..|        :.|....|:      |.:..:.||||...|
  Rat   461 LMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTE------KTRELVLKGIPERMR 519

  Fly    77 PDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEI------SDSISIDLPRTFPDNIHF--DMKKQ 133
            .::|:.:|||...:...|..:.:|:     :|.:      ::.|..||.|:.|::..|  :|...
  Rat   520 GELWLLLSGAINEKATHPGYYEDLV-----EKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIA 579

  Fly   134 RLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRD 198
            .|..:|.|||..|.::||||.:|.:..:||:...:|| :||||..:.|.::|.|::..:...|.|
  Rat   580 ALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEE-AFWLLVALCERMLPDYYNTRVVGALVD 643

  Fly   199 LAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRA 263
            ..||.||....:|.:...:.:||: ...|:..||:.:|..|:|.|:.:.:.||.|.||.|::|:.
  Rat   644 QGVFEELARDYVPQLYDCMQDLGV-ISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQL 707

  Fly   264 ALTMFVTHKNAILGC-DDIAALANLFR 289
            ||.:...:.:.:||| ||..|:..|.|
  Rat   708 ALAVLDANVDKLLGCKDDGEAMTVLGR 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	66/216 (31%)
Tbc1d9	XP_006255308.1	PH-GRAM1_TCB1D9_TCB1D9B	157..255	CDD:275420
		PH-GRAM2_TCB1D9_TCB1D9B	304..399	CDD:270161
		TBC	510..720	CDD:214540	66/216 (31%)
		EFh	<891..921	CDD:298682
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810