DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and Rabgap1l

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_006496938.1	Gene:	Rabgap1l / 29809	MGIID:	1352507	Length:	1051	Species:	Mus musculus

Alignment Length:	228	Identity:	66/228 - (28%)
Similarity:	114/228 - (50%)	Gaps:	11/228 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 IRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEISDSISIDLPRTFPDNIHFDMK 131
            ::.|:|...|.:||..::|....|... |.:|.|:..:...:.:   |:.|:.||||.:.:|...
Mouse   535 VKSGVPEALRAEVWQLLAGCHDNQEML-DKYRILITKDSAQESV---ITRDIHRTFPAHDYFKDT 595

  Fly   132 ----KQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENI-VPQYHSHN 191
                ::.||.|..||:..:.|:|||||.:::|.:||:.. .||::|.:|..|:... :...:.:|
Mouse   596 GGDGQESLYKICKAYSVFDEDIGYCQGQSFLAAVLLLHM-PEEQAFCVLVTIMYGYKLRDLYRNN 659

  Fly   192 MANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEG 256
            ..:|........:|:..::|.:..|..:|.|...:.||:||:.:|....|:..|..|.|.:..||
Mouse   660 FEDLHCKFYQLEKLMQEQLPDLYSHFCDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEG 724

  Fly   257 YKIVFRAALTMFVTHKNAILGCDDIAALANLFR 289
            ..|:|..||.:..|.|..:|..|...|| ..||
Mouse   725 LNIIFHVALALLKTSKEDLLQADFEGAL-KFFR 756

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	60/213 (28%)
Rabgap1l	XP_006496938.1	PTB_Rab6GAP	129..257	CDD:269922
		DUF3694	290..421	CDD:372133
		RabGAP-TBC	541..744	CDD:366170	58/207 (28%)
		Smc	<814..>1019	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810