DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and Tbc1d17

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001099728.1	Gene:	Tbc1d17 / 292886	RGDID:	1309686	Length:	646	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	59/275 - (21%)
Similarity:	118/275 - (42%)	Gaps:	64/275 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 KFMDGYLKTLTRRRMKWEAILQQNTDLTQVDAKLKRYIRKGIPGPYRPDV-WMKISGAAAAQRRS 93
            ||:.|||        .||:..:::          |.::||.....:|..: |..:|  |..:||:
  Rat   322 KFLLGYL--------SWESSAEEH----------KAHVRKKTDEYFRMKLQWKSVS--AEQERRN 366

  Fly    94 PDL--FRNLLRTEPFDKEISDSISIDLPRTF---PDNIHFDMKKQRLYNILIAYAHHNRDVGYCQ 153
            ..|  :|:|:     ::::|.:   |....|   |:|....:    |.:||:.|..::.|:||.|
  Rat   367 SLLHGYRSLI-----ERDVSRT---DRTNKFYEGPENPGLGL----LNDILLTYCMYHFDLGYVQ 419

  Fly   154 GLNYIAGLLLIVTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRI---PAVNR 215
            |::.:...:|.|..:|..:||.....:| :|......:...:.|.|.  :.|::.|:   |..:
  Rat   420 GMSDLLSPILFVVQNEVDAFWCFCGFME-LVHGNFEESQETMKRQLG--QLLLLLRVLDQPLCD- 480

  Fly   216 HVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFA--EGYKIVFRAALTMFVTHKNAILGC 278
            .:|:..........:|.:..|....|...|||:|:.::.  .|..:             :.::.|
  Rat   481 FLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNL-------------HLLVAC 532

  Fly   279 DDIAALANLFRDTMI 293
                |:.::.|||::
  Rat   533 ----AILDMERDTLM 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	46/219 (21%)
Tbc1d17	NP_001099728.1	DUF3548	3..218	CDD:192931
Tbc1d17	NP_001099728.1	TBC	308..543	CDD:214540	59/273 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810