DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5916 and SGSM3

DIOPT Version :9

Sequence 1:NP_001287357.1 Gene:CG5916 / 41960 FlyBaseID:FBgn0038401 Length:330 Species:Drosophila melanogaster
Sequence 2:XP_024307987.1 Gene:SGSM3 / 27352 HGNCID:25228 Length:820 Species:Homo sapiens


Alignment Length:301 Identity:86/301 - (28%)
Similarity:150/301 - (49%) Gaps:27/301 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 DEYGFK----RGDHFDYNNYSKFMDGYLKTLTRRRMKWEAILQ--QNTDLTQV-----------D 60
            ||:||:    .||.   ...|...:..|.....:|::|:|.|:  .|.|:..:           .
Human    43 DEFGFRVYKEEGDE---PGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRS 104

  Fly    61 AKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEI-SDSISIDLPRTFPD 124
            .||:..:..|||...||.:||::|||...:|.|...:|.:::....|:.| :..|..||.||.|.
Human   105 EKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPS 169

  Fly   125 NIHF----DMKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENIVP 185
            |..|    .:...||..:|.|.|....::|||||...:|..||:.. :||.:||::..|:|:::|
Human   170 NACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFL-EEEDAFWMMSAIIEDLLP 233

  Fly   186 -QYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIW 249
             .|.|..:..:..|..|.|.|:::.:|.:::.:....:...:|...||:..||.|:.::.:||||
Human   234 ASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIW 298

  Fly   250 DCVFAEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFRD 290
            |..|.||.:::|:..|.|....:..::..::.|::.|...|
Human   299 DLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSD 339

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5916NP_001287357.1 TBC 67..276 CDD:214540 67/214 (31%)
SGSM3XP_024307987.1 TBC 114..325 CDD:214540 67/211 (32%)
SH3_SGSM3 555..607 CDD:212747
RUN 634..785 CDD:308412
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1162786at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R540
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.850

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