Protein Alignment CG5916 and RABGAP1

DIOPT Version :10

• Sequence 1: NP_650524.1
• Gene: CG5916 / 41960
• FlyBaseID: FBgn0038401
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_036329.3
• Gene: RABGAP1 / 23637
• HGNCID: 17155
• Length: 1069
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 76/294 - (25%)
• Similarity: 136/294 - (46%)
• Gaps: 43/294 - (14%)

  Fly    46 WEAILQQ-NTDLTQVDAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDL---FRNLLRTE-P 105
            |..:|.: :.:|.....:|...:|.|:|...|.:||..::|.    ..:..|   :|.|:..| |
Human   541 WGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGC----HNNDHLVEKYRILITKESP 601

  Fly   106 FDKEISDSISIDLPRTFPDNIHFDMK----KQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVT 166
            .|    .:|:.|:.||||.:.:|...    :..||.|..||:.::.::|||||.:::|.:||:..
Human   602 QD----SAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHM 662

  Fly   167 DDEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKW 231
            .:|:....|:|.:.:..:.:....|..:|.........|:...||.:..|..::.|...:.||:|
Human   663 PEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQW 727

  Fly   232 FICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFRDTMIQDN 296
            |:.:|....|:..|..|.|.:..||..::|..||.:..|.|      ||:
Human   728 FLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSK------DDL--------------- 771

  Fly   297 IVTDCHGFVEAMFSLRLK---RSELESLRKVAVL 327
            ::||..|.:: .|.::|.   ||| |:.:|:..|
Human   772 LLTDFEGALK-FFRVQLPKRYRSE-ENAKKLMEL 803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_650524.1	TBC	67..276	CDD:214540	59/216 (27%)
RABGAP1	NP_036329.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..79
		PTB_Rab6GAP	145..273	CDD:269922
		DUF3694	307..437	CDD:463599
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	482..527
		TBC	563..772	CDD:214540	61/237 (26%)
		SMC_prok_B	<825..>1032	CDD:274008