Protein Alignment CG5916 and TBC1D9

DIOPT Version :10

• Sequence 1: NP_650524.1
• Gene: CG5916 / 41960
• FlyBaseID: FBgn0038401
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_055945.2
• Gene: TBC1D9 / 23158
• HGNCID: 21710
• Length: 1266
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 82/287 - (28%)
• Similarity: 138/287 - (48%)
• Gaps: 46/287 - (16%)

  Fly    36 LKTLTRRR----------------MKW--------EAILQQNTDLTQVDAKLKRYIRKGIPGPYR 76
            |.|:.|||                ..|        :.|....|:      |.:..:.||||...|
Human   463 LMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTE------KTRELVLKGIPESMR 521

  Fly    77 PDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEI------SDSISIDLPRTFPDNIHF--DMKKQ 133
            .::|:.:|||...:...|..:.:|:     :|.:      ::.|..||.|:.|::..|  :|...
Human   522 GELWLLLSGAINEKATHPGYYEDLV-----EKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIA 581

  Fly   134 RLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENIVPQYHSHNMANLLRD 198
            .|..:|.|||..|.::||||.:|.:..:||:...:|| :||||..:.|.::|.|::..:...|.|
Human   582 ALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEE-AFWLLVALCERMLPDYYNTRVVGALVD 645

  Fly   199 LAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRA 263
            ..||.||....:|.:...:.:||: ...|:..||:.:|..|:|.|:.:.:.||.|.||.|::|:.
Human   646 QGVFEELARDYVPQLYDCMQDLGV-ISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQL 709

  Fly   264 ALTMFVTHKNAILGC-DDIAALANLFR 289
            ||.:...:.:.:|.| ||..|:..|.|
Human   710 ALAVLDANVDKLLNCKDDGEAMTVLGR 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_650524.1	TBC	67..276	CDD:214540	66/216 (31%)
TBC1D9	NP_055945.2	PH-GRAM1_TCB1D9_TCB1D9B	157..255	CDD:275420
		PH-GRAM2_TCB1D9_TCB1D9B	304..399	CDD:270161
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	415..456
		TBC	512..722	CDD:214540	66/216 (31%)
		EFh	<893..923	CDD:415501
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1075..1095
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1132..1164