DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and tbc-11

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_508178.2	Gene:	tbc-11 / 180444	WormBaseID:	WBGene00018075	Length:	934	Species:	Caenorhabditis elegans

Alignment Length:	298	Identity:	80/298 - (26%)
Similarity:	132/298 - (44%)	Gaps:	44/298 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 WEAILQ---QNTDLTQVDAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFR--NLLRTEP 105
            |:.:::   |.:|..|   |:...:..|||...|..||..:|.........|||..  ::..::|
Worm   398 WDQLIENWDQQSDRPQ---KISELVLDGIPDKLRGRVWQLLSNVRILAIDQPDLVEKYHIFLSQP 459

  Fly   106 FDKEISDSISIDLPRTFPDNIHFDMK----KQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVT 166
            ...|  ..|..|:.||||.:.:|...    :|.||.|...|:.::.:|.|||||:::|..||:..
Worm   460 CPSE--QVIMRDIHRTFPAHDYFKESQGKGQQSLYKISKVYSLYDEEVSYCQGLSFLAASLLLHM 522

  Fly   167 DDEEKSFWLLKHIVENIVPQYHSHNMANLLRDL--AVFRELVIR----------RIPAVNRHVDN 219
             .||::|..|..|:.|..           ||||  ..|..|.:|          .||.::.|:::
Worm   523 -PEEQAFCTLVKIMFNYG-----------LRDLFKLGFDNLHLRFFQLTALLKDYIPDLSHHLEH 575

  Fly   220 LGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCDDIAAL 284
            :|:...:.||:||:.:|....|::.|..|.|...::|...:|..:|.:....|..:|..|....|
Worm   576 IGIETHMYASQWFLTLFTAKFPLQMVFFILDLFLSQGMNTIFHISLALLDDAKTDLLQLDFEGTL 640

  Fly   285 ANLFRDTM---IQDNIVTDCHGFVEAMFSLRLKRSELE 319
             ..||.::   .:....|.|  .:......||..|:||
Worm   641 -KYFRVSLPRKYRTEASTKC--LIHKAVKFRLNHSKLE 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	63/226 (28%)
tbc-11	NP_508178.2	PH-like	11..147	CDD:388408
		DUF3694	183..293	CDD:372133
		TBC	419..632	CDD:214540	63/226 (28%)
		Smc	<697..>901	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910