DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and tbc-9

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_502598.2	Gene:	tbc-9 / 178316	WormBaseID:	WBGene00012868	Length:	1247	Species:	Caenorhabditis elegans

Alignment Length:	268	Identity:	88/268 - (32%)
Similarity:	136/268 - (50%)	Gaps:	20/268 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 RMKWEAILQQ-NTDLTQV-DAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEP 105
            |.||...||: .|.:... ..:|.|.:.:|:|...|..:||..|||||....:|..:|.||....
Worm   460 REKWNKYLQEYGTGVCMYRTVELHRLLLEGVPLQLRGQIWMVCSGAAAEMALNPGYYRELLHKNQ 524

  Fly   106 FDKEIS-DSISIDLPRTFPDNIHFDMKK--QRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTD 167
            ....:: :.|..||.|:.|::..|....  ..|..||.|||..|.::||||.:|.:..:||:.|.
Worm   525 GVYSVALEEIERDLHRSLPEHPAFQQGPGIDALRRILTAYAFRNPNIGYCQAMNIVGSVLLLFTK 589

  Fly   168 DEEKSFWLLKHIVENIVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWF 232
            :|| :||||..:.|.::|.|::..:...|.|..||.|||.|.:|.|...:..|||. .::|..||
Worm   590 EEE-AFWLLVAVCERLLPDYYNTKVVGALVDQGVFSELVERLLPTVGAQLTRLGLD-DMVALSWF 652

  Fly   233 ICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGC---DDIAALANLFR----- 289
            :.:|...:..:..:||.|..|.||.:::|:.||.|.  .:|..|.|   ||...|.:|.:
Worm   653 LTVFLSAIKFDAAVRILDLFFFEGARLMFQVALEML--KENEKLICESRDDGEILMSLAKYTESI 715

  Fly   290 ---DTMIQ 294
               ||:::
Worm   716 YEGDTVVE 723

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	72/211 (34%)
tbc-9	NP_502598.2	PH-GRAM1_TCB1D9_TCB1D9B	154..253	CDD:275420
		PH-GRAM2_TCB1D9_TCB1D9B	309..406	CDD:270161
		TBC	489..695	CDD:214540	72/209 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940