Protein Alignment CG5916 and TBC1D3E

DIOPT Version :9

• Sequence 1: NP_001287357.1
• Gene: CG5916 / 41960
• FlyBaseID: FBgn0038401
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_001278395.1
• Gene: TBC1D3E / 102723859
• HGNCID: 27071
• Length: 549
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 79/327 - (24%)
• Similarity: 132/327 - (40%)
• Gaps: 50/327 - (15%)

  Fly     2 DATASSKFSDVDEYGFKRGDHFDYNNYSKFMDGYLK--TLTRRRMKWEAILQQNTDLTQVDAKLK 64
            :.:..||:.|:      .||...|.:..|.:|...|  .:..|...|..:|  ||:    :.|||
Human    71 EISRKSKWVDM------LGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLL--NTE----EMKLK 123

  Fly    65 RYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEISDSISIDLPRTFPDNIHFD 129
            .      ||.|:   .||..|..:::           ..:..|:::|.::...:  .|.|  .:.
Human   124 N------PGRYQ---IMKEKGKKSSE-----------HIQRIDRDVSGTLRKHI--FFRD--RYG 164

  Fly   130 MKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIV---ENIVPQYHSHN 191
            .|::.|.:||:||..:|.:||||:.|::||.|.|:.. .||.:||.|..::   .:.:..:||.|
Human   165 TKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYL-PEEDAFWALVQLLASERHSLQGFHSPN 228

  Fly   192 MANL--LRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDCVFA 254
            ...:  |:|..  ..:|....|....|.|...|..........|.|..:.:.:...||:||....
Human   229 GGTVQGLQDQQ--EHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLV 291

  Fly   255 EGYKIVFRAALTMFVTHKNAIL---GCDDIAALANLFRDTMIQDNIVTDCHGFVEAMFSLRLKRS 316
            ||.:.:.......|...:..:.   .|...|...|.|.||..:|......| ...:|..|..|:.
Human   292 EGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKH-LRASMKKLTRKKG 355

  Fly   317 EL 318
            :|
Human   356 DL 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	50/213 (23%)
TBC1D3E	NP_001278395.1	TBC	99..312	CDD:214540	59/245 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	350..419		3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810