DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and tbc1d10b

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_002940627.3	Gene:	tbc1d10b / 100493619	XenbaseID:	XB-GENE-940041	Length:	1337	Species:	Xenopus tropicalis

Alignment Length:	325	Identity:	102/325 - (31%)
Similarity:	151/325 - (46%)	Gaps:	44/325 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ASSKFSD----------VDEYGFKRGDHFDYNNYSKFMDGYLKT-LTRRR-MKW-EAILQQNTDL 56
            |||..||          .|:|||..|     |.||...:|:|.. ::|:| :|| :.....:..|
Frog   811 ASSLGSDSEINGIPYRKTDKYGFLGG-----NQYSGNGEGFLSVEISRQRELKWLDMFSHWDKWL 870

  Fly    57 TQVDAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEISDSISIDLPRT 121
            ::...|:|...|||||...|...|..:|.:....|::|..|..:.| :|.|.:..|.|..||.|.
Frog   871 SRRFQKVKLRCRKGIPSSLRAKAWQLLSNSEELLRKNPGKFEEMER-QPGDPKWLDVIEKDLHRQ 934

  Fly   122 FPDNIHFDMK----KQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVEN 182
            ||.:..|..:    :|.||.||.||..:..:.||||....:|.:||:.. ..|::||.|..|.:.
Frog   935 FPFHEMFAARGGHGQQDLYRILKAYTVYRPEEGYCQAQAPVAAVLLMHM-PAEQAFWCLVQICDK 998

  Fly   183 IVPQYHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLR 247
            .:|.|:|..:..:..|..:|..|:.|..|...||:....:...:..::||:|||:..||..:|||
Frog   999 YLPGYYSAGLEAIQLDGEIFFALLRRVCPMAYRHLKKFKIDPILYMTEWFMCIFSRTLPWASVLR 1063

  Fly   248 IWDCVFAEGYKIVFRAALTMFVTHKNAILGCDDIAALANLFRDTMIQDNIVTDCHGFVEAMFSLR 312
            :||..|.||.|||||..|.                    |.:.|:...:.:..|.|..|.|..||
Frog  1064 VWDMFFCEGIKIVFRVGLV--------------------LLKHTLGSVDKLRSCQGMYETMEKLR 1108

Fly 313 312
Frog 1109 1108

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	72/212 (34%)
tbc1d10b	XP_002940627.3	PSII_BNR	155..471	CDD:421885
		PLN03131	<505..>698	CDD:178677
		TBC	881..1086	CDD:214540	73/226 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000