DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5916 and sgsm3

DIOPT Version :9

Sequence 1:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001123837.1	Gene:	sgsm3 / 100170594	XenbaseID:	XB-GENE-965522	Length:	753	Species:	Xenopus tropicalis

Alignment Length:	330	Identity:	93/330 - (28%)
Similarity:	163/330 - (49%)	Gaps:	39/330 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DEYGFKRGDHFD--YNNYSKFMDGYLKTLTRRRMKWEAILQ--QNTDL-----TQVDA------K 62
            ||:|| |.|..|  ..|.||.:...|....::|::|:|.|:  .|.|:     .::|.      |
Frog    44 DEFGF-RVDKEDGAEPNSSKLLGIPLTEDPQQRLRWQAHLEFTHNHDVGDLTWDKIDVTLPHSDK 107

  Fly    63 LKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKEI-SDSISIDLPRTFPDNI 126
            |:..:..|||...||.:||::|||...::.|...:::::|....|..: :..|..||.||.|.|.
Frog   108 LRSLVLAGIPHSMRPQLWMRLSGALQKKQNSEMTYKDIVRNSSNDDTLAAKQIEKDLLRTMPSNA 172

  Fly   127 HFDMKKQ----RLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEEKSFWLLKHIVENIVP-Q 186
            .|...:.    ||..:|...|....|:|||||...:|..||:.. :||.:||::..|||::|| .
Frog   173 CFSNLQSVGVPRLRRVLRGLAWLYPDIGYCQGTGMVAACLLLFL-EEEDAFWMMAAIVEDLVPVS 236

  Fly   187 YHSHNMANLLRDLAVFRELVIRRIPAVNRHVDNLGLPYPVIASKWFICIFAEVLPVETVLRIWDC 251
            |.:..:..:..|..|.|.|:::.:|.:::.:....:...:|...||:..||.|:.::.:|||||.
Frog   237 YFNTTLVGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVHIKLLLRIWDF 301

  Fly   252 VFAEGYKIVFRAALTMFVTHKNAILGCDDIAALAN--------------LFRDTMIQDNIVTDCH 302
            .|.:|..::|:..|.|....:..::..::.|::.|              |.|:.|:....:|:.
Frog   302 FFYQGSLVLFQTTLGMLKMKEEELIQSENSASIFNTLSDIPSQIEEADVLLREAMLISGTLTEV- 365

  Fly   303 GFVEA 307
             .:||
Frog   366 -MIEA 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	65/214 (30%)
sgsm3	NP_001123837.1	TBC	115..326	CDD:214540	65/211 (31%)
		SH3_SGSM3	486..538	CDD:212747
		RUN	565..716	CDD:367169
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1162786at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R540
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950