Protein Alignment Sb and Tmprss5

DIOPT Version :10

• Sequence 1: NP_476709.1
• Gene: Sb / 41958
• FlyBaseID: FBgn0003319
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001346389.1
• Gene: Tmprss5 / 80893
• MGIID: 1933407
• Length: 455
• Species: Mus musculus
• Alignment Length: 320
• Identity: 109/320 - (34%)
• Similarity: 159/320 - (49%)
• Gaps: 52/320 - (16%)

  Fly   475 SSSSSGIVTSSQRPTQPTHRTPVLATSGIETNEISDSSIPDAGALGHVKTISAARSECGVPTLAR 539
            |:...|:|..|.:|:                     ::.|..      :.:|...||||...||
Mouse   179 SARPGGLVEESWKPS---------------------ANCPSG------RIVSLKCSECGARPLA- 215

  Fly   540 PETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLLISQI---R 601
              :|||||::.|.||||||.||.      ..|.|.||.:::..:|:.||.||:....:|::   |
Mouse   216 --SRIVGGQAVASGRWPWQASVM------LGSRHTCGASVLAPHWVVTAAHCMYSFRLSRLSSWR 272

  Fly   602 IRVGEYDFSHVQEQLPYIERG--VAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLPET 664
            :..|......|::     .:|  |.|.:.||.||...::||:||::|..|:.|:..|..:|||..
Mouse   273 VHAGLVSHGAVRQ-----HQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVGAVCLPAK 332

  Fly   665 DS-LLIGMNATVTGWGRLSEGGTLPS-VLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYE 727
            :. ...|....|:|||......|..| .||:..||::|...|.|..|.:|.   :....|||||.
Mouse   333 EQHFPWGSQCWVSGWGHTDPSHTHSSDTLQDTMVPLLSTYLCNSSCMYSGA---LTHRMLCAGYL 394

  Fly   728 TGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWILEHVR 787
            .|..|:|||||||||...|.| .:.|.|::|||.||||.|.|||..::::|..||.:.|:
Mouse   395 DGRADACQGDSGGPLVCPSGD-TWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWIHDTVQ 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_476709.1	Tryp_SPc	544..785	CDD:238113	94/247 (38%)
Tmprss5	NP_001346389.1	SRCR_2	116..213	CDD:464747	11/60 (18%)
		Tryp_SPc	217..448	CDD:214473	93/245 (38%)