DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sb and prss60.1

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	261	Identity:	101/261 - (38%)
Similarity:	151/261 - (57%)	Gaps:	14/261 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   525 ISAARSECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAG 589
            :..:.|:..|..||....|||||.:|..|.||||||:....:.|    |.|||:|||..|:.||.
Zfish    15 VQGSHSQLNVCGLAPLNNRIVGGVNAFDGSWPWQVSLHSPIYGG----HFCGGSLINSEWVLTAA 75

  Fly   590 HCVDDLLISQIRIRVGEYDFSHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAP 654
            ||:..:..|.:.:.:|:.....|...  .|.|.|:...|||.|:.||.|.|:||:.|...:.|:.
Zfish    76 HCLPRITTSSLLVFLGKTTQQGVNTY--EINRTVSVITVHPSYNNLTNENDIALLHLSSAVTFSN 138

  Fly   655 HVSPICLPETDSLL-IGMNATVTGWGRLSEGGTLPS--VLQEVSVPIVSNDNCKSMFMRAGRQEF 716
            ::.|:||...:|:. .|.::.:||||.:..|..||:  :|||..:|:|.||.|.:: :.:|.
Zfish   139 YIRPVCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQCNAL-LGSGS--- 199

  Fly   717 IPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPW 781
            :.:..:|||...||:|:||||||||:.:| |...:..:||.|||.|||:...|||.||:|::..|
Zfish   200 VTNNMICAGLLQGGRDTCQGDSGGPMVSK-QCLVWVQSGITSWGYGCADPYSPGVYTRVSQYQSW 263

  Fly   782 I 782
            |
Zfish   264 I 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	95/241 (39%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	96/242 (40%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	95/241 (39%)
		Tryp_SPc	34..267	CDD:238113	96/242 (40%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810