DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sb and ST14

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_068813.1	Gene:	ST14 / 6768	HGNCID:	11344	Length:	855	Species:	Homo sapiens

Alignment Length:	263	Identity:	102/263 - (38%)
Similarity:	153/263 - (58%)	Gaps:	21/263 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   531 ECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHC-VDD 594
            :||:.:..| :.|:|||..|..|.||||||:.     .....|.||.:||:.||:.:|.|| :||
Human   603 DCGLRSFTR-QARVVGGTDADEGEWPWQVSLH-----ALGQGHICGASLISPNWLVSAAHCYIDD 661

  Fly   595 LLI-----SQIRIRVGEYDFSHVQEQLPYIERGVAKKVV-HPKYSFLTYEYDLALVKLEQPLEFA 653
            ...     :|....:|.:|.|  |...|.::....|::: ||.::..|::||:||::||:|.|::
Human   662 RGFRYSDPTQWTAFLGLHDQS--QRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYS 724

  Fly   654 PHVSPICLPETDSLL-IGMNATVTGWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFI 717
            ..|.|||||:...:. .|....|||||....|||...:||:..:.:::...|:::.    .|:..
Human   725 SMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLL----PQQIT 785

  Fly   718 PDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWI 782
            |.: :|.|:.:||.|||||||||||.:...|||.|.||::|||.|||:.|.|||.||:..|..||
Human   786 PRM-MCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLPLFRDWI 849

  Fly   783 LEH 785
            .|:
Human   850 KEN 852

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	96/246 (39%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	97/248 (39%)
ST14	NP_068813.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		SEA	88..>171	CDD:307516
		CUB	227..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	488..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060
		Tryp_SPc	615..852	CDD:238113	97/248 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143804
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40690
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740