Protein Alignment Sb and F12

DIOPT Version :10

• Sequence 1: NP_476709.1
• Gene: Sb / 41958
• FlyBaseID: FBgn0003319
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_067464.2
• Gene: F12 / 58992
• MGIID: 1891012
• Length: 597
• Species: Mus musculus
• Alignment Length: 323
• Identity: 96/323 - (29%)
• Similarity: 156/323 - (48%)
• Gaps: 53/323 - (16%)

  Fly   494 RTPVLATSGI-ETNEISDSSIPDAGALGHVKTISAARSECGVPTLARPET--------------- 542
            :||..|...: |:.|.|.|..|   :|.|....|....    .:|::..|
Mouse   296 QTPTFAPLVVPESQEESPSQAP---SLSHAPNDSTDHQ----TSLSKTNTMGCGQRFRKGLSSFM 353

  Fly   543 RIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDL-LISQIRIRVGE 606
            |:|||..|..|..|:..::    ::|   .:.|.|:||...|:.||.||:.:. ...::.:.:|:
Mouse   354 RVVGGLVALPGSHPYIAAL----YWG---NNFCAGSLIAPCWVLTAAHCLQNRPAPEELTVVLGQ 411

  Fly   607 YDFSHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLE-----FAPHVSPICLPE--- 663
            ...:...|....:  .|....:|..:|.:||::||||::|::...     .:|||.|:|||.
Mouse   412 DRHNQSCEWCQTL--AVRSYRLHEGFSSITYQHDLALLRLQESKTNSCAILSPHVQPVCLPSGAA 474

  Fly   664 --TDSLLIGMNATVTGWGRLSEGG-TLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAG 725
              ::::|    ..|.|||...||. ...:.|||..||.::.|.|.:..:..  ...:|.: ||||
Mouse   475 PPSETVL----CEVAGWGHQFEGAEEYSTFLQEAQVPFIALDRCSNSNVHG--DAILPGM-LCAG 532

  Fly   726 YETGGQDSCQGDSGGPL--QAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWILEHV 786
            :..||.|:|||||||||  :..:.:.:..|.|:||||.||.:.|.|||.|.::.:..||.:|:
Mouse   533 FLEGGTDACQGDSGGPLVCEEGTAEHQLTLRGVISWGSGCGDRNKPGVYTDVANYLAWIQKHI 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_476709.1	Tryp_SPc	544..785	CDD:238113	81/254 (32%)
F12	NP_067464.2	FN2	41..88	CDD:238019
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		KR	217..295	CDD:412161
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..338		9/38 (24%)
		Tryp_SPc	355..594	CDD:238113	81/254 (32%)