DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sb and prss60.2

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	256	Identity:	98/256 - (38%)
Similarity:	149/256 - (58%)	Gaps:	21/256 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   532 CGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLL 596
            ||...|   .:|||||.:|..|.||||||::...:.|    |.|||:||:..|:.||.||:..:.
Zfish    25 CGQAPL---NSRIVGGVNAPEGSWPWQVSLQSPRYGG----HFCGGSLISSEWVLTAAHCLPGVS 82

  Fly   597 ISQIRIRVGEYDFSHVQEQLPYIE--RGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPI 659
            .|.:.:.:|.    ..|:.:...|  |.|||.:||..|:..|.:.|:||::|...:.|..::.|:
Zfish    83 ESSLVVYLGR----RTQQGVNTHETSRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPV 143

  Fly   660 CLPETDSLL-IGMNATVTGWGRLSEGGTLPS--VLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIF 721
            ||...:|:. .|.::.:||||.:..|..||:  :|||..:|:|:||.|.:. :.:|.   :.:..
Zfish   144 CLAAQNSVYSAGTSSWITGWGDVQAGVNLPAPGILQETMIPVVANDRCNAQ-LGSGT---VTNNM 204

  Fly   722 LCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWI 782
            :|||...||:|:||||||||:..:... .:..|||.|||.|||:.|.|||.||:|::..||
Zfish   205 ICAGLAKGGKDTCQGDSGGPMVTRLCT-VWIQAGITSWGYGCADPNSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	93/243 (38%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	94/244 (39%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	93/243 (38%)
		Tryp_SPc	34..267	CDD:238113	94/244 (39%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810