DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sb and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_001025468.1	Gene:	Tmprss11c / 435845	MGIID:	3521861	Length:	431	Species:	Mus musculus

Alignment Length:	277	Identity:	97/277 - (35%)
Similarity:	142/277 - (51%)	Gaps:	23/277 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   507 EISDSSIPDAGALGHVKTISAARSECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSS 571
            :.||.::|.|..|        ..:.||..|:.....::.||:.|..|.||||.|:::      :|
Mouse   171 KFSDIAMPIAEDL--------LNTCCGRRTIIHRGHKVAGGQDAEEGEWPWQASLQQ------NS 221

  Fly   572 THRCGGALINENWIATAGHCVDDLLISQIRIRVGEYDFSHVQEQLPYIERGVAKKVVHPKYSFLT 636
            .||||..||:..|:.||.||    .|.....:..:..|..:..: |...|.|...::|..||:..
Mouse   222 VHRCGATLISNYWLITAAHC----FIRAANPKDWKVSFGFLLSK-PQAPRAVKNIIIHENYSYPA 281

  Fly   637 YEYDLALVKLEQPLEFAPHVSPICLPE-TDSLLIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVS 700
            ::.|:|:|:|..|:.:..::...|||| |.......:..|||||.|...|..|::||:..|.|:.
Mouse   282 HDNDIAVVRLSSPVLYESNIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGKVKIID 346

  Fly   701 NDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAE 765
            |..|.|.....|   .|....:|||:..|..|:|||||||||.::...|.:|||||:|||..||.
Mouse   347 NKTCNSGKAYGG---MITPGMMCAGFLKGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECAL 408

  Fly   766 ANLPGVCTRISKFTPWI 782
            .|.|||.||::.:..||
Mouse   409 PNKPGVYTRVTYYRDWI 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	87/239 (36%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	89/240 (37%)
Tmprss11c	NP_001025468.1	SEA	62..157	CDD:279699
		Tryp_SPc	199..425	CDD:214473	87/239 (36%)
		Tryp_SPc	200..428	CDD:238113	89/240 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834036
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8807
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840