DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sb and Tmprss9

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	365	Identity:	119/365 - (32%)
Similarity:	178/365 - (48%)	Gaps:	51/365 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   424 RRTTTPTTTTR-RTTTNKPTRPYQRPTTATSSSSTSTTSSKTPTTTRPISSSSSSSSGIVTSSQR 487
            ||....|..|| |....:.|.....|...|::.:.:|.|:..||         |..|....:..:
Mouse   669 RRPGVYTRVTRLRDWILEVTSAADMPVVPTATPAPATPSTPWPT---------SPESWAPNTFAK 724

  Fly   488 PTQPTHRTPVLATSGIETNEISDSSIPDAGALGHVKTISAARSECGV-PTLARPETRIVGGKSAA 551
            ||......|:                       |..| :|...|||. |.:.:| ||||||.||.
Mouse   725 PTAAPSPVPL-----------------------HPST-TAKPQECGARPAMDKP-TRIVGGISAV 764

  Fly   552 FGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLLISQIRIRVGEYDFSHVQEQL 616
            .|..|||.|::.      ...|.||..::.:.|:.:|.||.:...:.|::..:|......|...
Mouse   765 SGEVPWQASLKE------GPRHFCGATVVGDRWLLSAAHCFNHTKVEQVQAHLGTVSLLGVGGS- 822

  Fly   617 PYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLP-ETDSLLIGMNATVTGWGR 680
            | ::.|:.:..:||:|:....::|:||::|.|||.|..::.|:||| ......:|....::|||.
Mouse   823 P-VKLGLRRVALHPRYNPGILDFDVALLELAQPLVFNKYIQPVCLPLAIHKFPVGRKCMISGWGN 886

  Fly   681 LSEG-GTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQA 744
            :.|| .|.|.:||:.||.|:....|.:::..:     :.|..||||:..|..|||||||||||..
Mouse   887 MQEGNATKPDILQKASVGIIEQKMCGALYNFS-----LTDRMLCAGFLEGRVDSCQGDSGGPLAC 946

  Fly   745 KSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWILE 784
            :...|.|:||||:|||||||:|..|||..||::...|||:
Mouse   947 EETPGVFYLAGIVSWGIGCAQAKKPGVYARITRLKDWILK 986

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	89/240 (37%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	91/243 (37%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473	6/14 (43%)
		Tryp_SPc	756..984	CDD:214473	89/240 (37%)
		Tryp_SPc	1085..1336	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834013
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740