DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sb and prss60.3

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	256	Identity:	98/256 - (38%)
Similarity:	149/256 - (58%)	Gaps:	21/256 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   532 CGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLL 596
            ||...|   .||||||.:|:.|.||||||:....:.|    |.|||:||:..|:.||.||:..:.
Zfish    27 CGQAPL---NTRIVGGVNASPGSWPWQVSLHSPKYGG----HFCGGSLISSEWVLTAAHCLSGVS 84

  Fly   597 ISQIRIRVGEYDFSHVQEQLPYIE--RGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPI 659
            .:.:.:.:|.    ..|:.:...|  |.|||..||..|:..|.:.|:||::|...:.|..::.|:
Zfish    85 ETTLVVYLGR----RTQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNYIRPV 145

  Fly   660 CLPETDSLL-IGMNATVTGWGRLSEGGTLPS--VLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIF 721
            ||...:|:. .|.::.:||||.:..|..||:  :|||..:|:|:||.|.:: :.:|.   :.:..
Zfish   146 CLAAQNSVYSAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRCNAL-LGSGT---VTNNM 206

  Fly   722 LCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWI 782
            :|||...||:|:||||||||:..:... .:..|||.|||.|||:.|.|||.||:|::..||
Zfish   207 ICAGLTQGGKDTCQGDSGGPMVTRLCT-VWVQAGITSWGYGCADPNSPGVYTRVSQYQSWI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	92/243 (38%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	93/244 (38%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	93/244 (38%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291432at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910