DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sb and Tmprss11g

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_796136.2	Gene:	Tmprss11g / 320454	MGIID:	2444058	Length:	417	Species:	Mus musculus

Alignment Length:	280	Identity:	96/280 - (34%)
Similarity:	144/280 - (51%)	Gaps:	27/280 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   510 DSSIPDAGALGHVKTISAAR------SECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFG 568
            |:|:|      :::.::||:      |:||......|..||..||.|....||||.|::
Mouse   152 DASLP------YLREMNAAQAEHILNSDCGSGMEYPPIARIADGKPADKASWPWQSSLQ------ 204

  Fly   569 FSSTHRCGGALINENWIATAGHCVDDLLISQIRIRVGEYDFSHVQEQLPYIERGVAKKVVHPKYS 633
            ....|.||.:||...|:.|:.||.|:..    ..::....|...... |...|.|...:||..|:
Mouse   205 VEGIHLCGASLIGSQWLVTSAHCFDNYK----NPKLWTVSFGRTLSS-PLTTRKVESIIVHENYA 264

  Fly   634 FLTYEYDLALVKLEQPLEFAPHVSPICLPE-TDSLLIGMNATVTGWGRLSEGGTLPSVLQEVSVP 697
            ...::.|:|:|||..|:.|:.::..:|||: |..:|......|||||.|...|..|:.||||.:.
Mouse   265 SHKHDDDIAVVKLSSPVLFSENLHRVCLPDATFQVLPKSKVFVTGWGALKANGPFPNSLQEVEIE 329

  Fly   698 IVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIG 762
            |:|||.|..:.:..|.   |....:|||:.||..|:|:|||||||.......:::|.||:||||.
Mouse   330 IISNDVCNQVNVYGGA---ISSGMICAGFLTGKLDACEGDSGGPLVISDNRNKWYLLGIVSWGID 391

  Fly   763 CAEANLPGVCTRISKFTPWI 782
            |.:.|.||:.||::.:..||
Mouse   392 CGKENKPGIYTRVTHYRDWI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	85/239 (36%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	86/240 (36%)
Tmprss11g	NP_796136.2	SEA	48..142	CDD:279699
		Tryp_SPc	185..411	CDD:214473	85/239 (36%)
		Tryp_SPc	186..414	CDD:238113	86/240 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834022
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840