DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sb and Tmprss3

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	112/277 - (40%)
Similarity:	145/277 - (52%)	Gaps:	35/277 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   520 GHVKTISAARSECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENW 584
            |||.|:..  |.||:.|...|  |||||..::..:||||||::      |...|.|||::|...|
  Rat   197 GHVVTLKC--SACGMRTGYSP--RIVGGNVSSLTQWPWQVSLQ------FQGYHLCGGSVITPLW 251

  Fly   585 IATAGHCVDDLLISQI-RIRVGEYDF------SHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLA 642
            |.||.|||.||...:. .::||....      ||:.|::.|          |.||.......|:|
  Rat   252 IVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIY----------HSKYKPKRLGNDIA 306

  Fly   643 LVKLEQPLEFAPHVSPICLPET-DSLLIGMNATVTGWGRLSEG-GTLPSVLQEVSVPIVSNDNCK 705
            |:||.:||.|...:.|||||.: ::...|.....:|||...:| |....||...:||::||..|.
  Rat   307 LMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGAGDASPVLNHAAVPLISNKICN 371

  Fly   706 SMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFF-LAGIISWGIGCAEANLP 769
            ...:..|   .|....|||||..||.|||||||||||..  |:.|.: |.|..|:||||||.|.|
  Rat   372 HRDVYGG---IISPSMLCAGYLKGGVDSCQGDSGGPLVC--QERRLWKLVGATSFGIGCAEVNKP 431

  Fly   770 GVCTRISKFTPWILEHV 786
            ||.|||:.|..||.|.:
  Rat   432 GVYTRITSFLDWIHEQL 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	100/248 (40%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	101/250 (40%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	7/15 (47%)
		Tryp_SPc	216..444	CDD:214473	100/248 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44824
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740