DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sb and Ovch2

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	XP_003749007.2	Gene:	Ovch2 / 308919	RGDID:	1564636	Length:	579	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	109/292 - (37%)
Similarity:	164/292 - (56%)	Gaps:	36/292 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   520 GHVKTISAARS-ECGVPTLARP--------ETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRC 575
            ||..|:|:.|: :|| .:|.:|        .:|||||.....|.:|||||:::      ...|.|
  Rat    20 GHSATLSSIRAPDCG-KSLVKPWPQNYFSLFSRIVGGSQVEKGSYPWQVSLKQ------KQKHIC 77

  Fly   576 GGALINENWIATAGHCVDDLLIS-QIRIRVGEYDFSHVQ--EQLPYIERGVAKKVVHPKYSF-LT 636
            ||.:|:..|:.||.||:.:..|: .:.:..||:|.|..:  ||...||    ..::||::|. ..
  Rat    78 GGTIISSQWVITAAHCMANRNIALTLNVTAGEHDLSQAEPGEQTLAIE----TIIIHPQFSTKKP 138

  Fly   637 YEYDLALVKLEQPLEFAPHVSPICLPET-DSLLIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVS 700
            ..||:||:|:....:|...|.|:||||. :....|...|..|||||||||:||.|||:|::||::
  Rat   139 MNYDIALLKMVGTFQFGQFVRPVCLPEPGEQFNAGYICTTAGWGRLSEGGSLPQVLQQVNLPILT 203

  Fly   701 NDNCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCA- 764
            ::.|:::.:.. |.......|||.|...||:|:|||||||.|..:::.|.:.|||:.|||:||.
  Rat   204 HEECEAVMLTL-RNPITGKTFLCTGSPDGGRDACQGDSGGSLMCQNRKGAWTLAGVTSWGLGCGR 267

  Fly   765 ---------EANLPGVCTRISKFTPWILEHVR 787
                     |...||:.|.:.:..|||.|||:
  Rat   268 SWRNNARKKEQGSPGIFTDLRRVLPWIHEHVQ 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	95/253 (38%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	96/255 (38%)
Ovch2	XP_003749007.2	Tryp_SPc	52..297	CDD:238113	96/255 (38%)
		CUB	317..420	CDD:238001
		CUB	431..541	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810