DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sb and Tmprss11f

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_848845.1	Gene:	Tmprss11f / 243083	MGIID:	2442348	Length:	439	Species:	Mus musculus

Alignment Length:	275	Identity:	89/275 - (32%)
Similarity:	133/275 - (48%)	Gaps:	48/275 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   530 SECG-------VPTLARPET-RIVGGKSAAF-GRWPWQVSVRRTSFFGFSSTHRCGGALINENWI 585
            |.||       :|..|...| |||.|:..|. |.||||.|::.     ..:.|:||..||:..|:
Mouse   185 SRCGIRMSSSNIPLPASSSTERIVQGRETAMEGEWPWQASLQL-----IGAGHQCGATLISNTWL 244

  Fly   586 ATAGHCVDDLLISQIRIRVGEYDFSHVQEQL------------PYIERGVAKKVVHPKYSFLTYE 638
            .||.||                 |...::..            |.::|.|.|.::|.:|...|.|
Mouse   245 LTAAHC-----------------FWKNRDPTKWIVTFGTTITPPLVKRSVGKIIIHEEYHRDTNE 292

  Fly   639 YDLALVKLEQPLEFAPHVSPICLPETDSLLIGMNAT-VTGWGRLSEGGTLPSVLQEVSVPIVSND 702
            .|:||.:|...:||:..|..:|||::...|....:. |||:|.:.:.|...:.|::..|..:.:|
Mouse   293 NDIALAQLTTRVEFSNVVQRVCLPDSSMKLPPKTSVFVTGFGSIVDDGPTQNKLRQARVETIGSD 357

  Fly   703 NCKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEAN 767
            .|....:..|   .|....||||:..|..|:|:|||||||...::| .:::.||:|||..||..|
Mouse   358 VCNRKDVYDG---LITPGMLCAGFMEGKIDACKGDSGGPLVYDNRD-IWYIVGIVSWGQSCALPN 418

  Fly   768 LPGVCTRISKFTPWI 782
            .|||.||::|:..||
Mouse   419 KPGVYTRVTKYRDWI 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	81/252 (32%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	82/253 (32%)
Tmprss11f	NP_848845.1	SEA	60..164	CDD:396113
Tmprss11f	NP_848845.1	Tryp_SPc	207..436	CDD:238113	82/253 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834044
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840