DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sb and Tmprss7

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	NP_766043.3	Gene:	Tmprss7 / 208171	MGIID:	2686594	Length:	829	Species:	Mus musculus

Alignment Length:	263	Identity:	96/263 - (36%)
Similarity:	133/263 - (50%)	Gaps:	25/263 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   532 CGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLL 596
            ||....:....|||||..:..|.||||||:.      |..:..||.::|:..|:.:|.||.....
Mouse   580 CGCSRSSSFLHRIVGGSDSQEGTWPWQVSLH------FVGSAYCGASVISREWLLSAAHCFHGNR 638

  Fly   597 ISQ---IRIRVGEYDFSHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLE--QPLEFAPHV 656
            :|.   ....:|.|    ||....:|. .|.:.|||..|:..|::||:||::|.  .|......:
Mouse   639 LSDPTPWTAHLGMY----VQGNAKFIS-PVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLI 698

  Fly   657 SPICLPET-DSLLIGMNATVTGWGRLSEGGTLPS-VLQEVSVPIVSNDNCKSMFMRAGRQEFIPD 719
            .|||:|.. ..:..|....||||||..|..:..| |||:..|.::....|.|.:      ..|..
Mouse   699 QPICIPPAGQKVRSGEKCWVTGWGRRHEADSKGSPVLQQAEVELIDQTVCVSTY------GIITS 757

  Fly   720 IFLCAGYETGGQDSCQGDSGGPLQA-KSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWIL 783
            ..||||..:|..|:|:|||||||.. :..||::.|.||:|||.||...|.|||.||:|.|.|||.
Mouse   758 RMLCAGVMSGKSDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGCGRPNFPGVYTRVSSFVPWIH 822

  Fly   784 EHV 786
            ::|
Mouse   823 KYV 825

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	91/246 (37%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	92/248 (37%)
Tmprss7	NP_766043.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..52
		SEA	94..194	CDD:366610
		CUB	<257..345	CDD:238001
		LDLa	470..504	CDD:238060
		LDLa	545..580	CDD:238060	96/263 (37%)
		Tryp_SPc	591..821	CDD:214473	91/246 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834010
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840