DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sb and St14

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	XP_036010597.1	Gene:	St14 / 19143	MGIID:	1338881	Length:	875	Species:	Mus musculus

Alignment Length:	265	Identity:	99/265 - (37%)
Similarity:	150/265 - (56%)	Gaps:	25/265 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   531 ECGVPTLARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDL 595
            :||:.:..: :.|:|||.:|..|.||||||:.     .....|.||.:||:.:|:.:|.||..|
Mouse   623 DCGLRSFTK-QARVVGGTNADEGEWPWQVSLH-----ALGQGHLCGASLISPDWLVSAAHCFQD- 680

  Fly   596 LISQIRIRVGEYD----FSHVQEQLPYIERGV----AKKVV-HPKYSFLTYEYDLALVKLEQPLE 651
               ....:..:|.    |..:.:|......||    .|::: ||.::..|::||:||::||:.:|
Mouse   681 ---DKNFKYSDYTMWTAFLGLLDQSKRSASGVQELKLKRIITHPSFNDFTFDYDIALLELEKSVE 742

  Fly   652 FAPHVSPICLPE-TDSLLIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQE 715
            ::..|.|||||: |.....|....|||||...||||...:||:..:.:::...|:.:.    .|:
Mouse   743 YSTVVRPICLPDATHVFPAGKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCEDLM----PQQ 803

  Fly   716 FIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTP 780
            ..|.: :|.|:.:||.|||||||||||.:..:|||.|.||::|||.|||:.|.|||.||:.....
Mouse   804 ITPRM-MCVGFLSGGVDSCQGDSGGPLSSAEKDGRMFQAGVVSWGEGCAQRNKPGVYTRLPVVRD 867

  Fly   781 WILEH 785
            ||.||
Mouse   868 WIKEH 872

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	93/248 (38%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	94/250 (38%)
St14	XP_036010597.1	SEA	108..198	CDD:396113
		CUB	247..352	CDD:238001
		CUB	360..464	CDD:238001
		LDLa	474..506	CDD:238060
		LDLa	512..543	CDD:238060
		LDLa	545..579	CDD:238060
		LDLa	587..622	CDD:238060
		Tryp_SPc	635..872	CDD:238113	94/250 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834032
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740