Protein Alignment Sb and CFD

DIOPT Version :10

• Sequence 1: NP_476709.1
• Gene: Sb / 41958
• FlyBaseID: FBgn0003319
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 73/247 - (29%)
• Similarity: 116/247 - (46%)
• Gaps: 20/247 - (8%)

  Fly   538 ARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTHRCGGALINENWIATAGHCVDDLLISQIRI 602
            |.|..||:||:.|.....|:..||:      .:..|.|||.|:.|.|:.:|.||::|....::::
Human    27 APPRGRILGGREAEAHARPYMASVQ------LNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQV 85

  Fly   603 RVGEYDFSHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLPETD-S 666
            .:|.:..|..:......:  |.:.|.||.....|.::||.|::|.:.....|.|.|:.....| .
Human    86 LLGAHSLSQPEPSKRLYD--VLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRD 148

  Fly   667 LLIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQ 731
            :..|....|.|||.::..|..|..||.|.:|::....|.   .|......|.:..:||  |:..:
Human   149 VAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN---RRTHHDGAITERLMCA--ESNRR 208

  Fly   732 DSCQGDSGGPLQAKSQDGRFFLAGIISWGIG-CAEANLPGVCTRISKFTPWI 782
            |||:|||||||....     .|.|:::.|.. |.....||:.||::.:..||
Human   209 DSCKGDSGGPLVCGG-----VLEGVVTSGSRVCGNRKKPGIYTRVASYAAWI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_476709.1	Tryp_SPc	544..785	CDD:238113	70/241 (29%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	70/241 (29%)