DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sb and tmprss12

DIOPT Version :9

Sequence 1:	NP_001287355.1	Gene:	Sb / 41958	FlyBaseID:	FBgn0003319	Length:	787	Species:	Drosophila melanogaster
Sequence 2:	XP_031751504.1	Gene:	tmprss12 / 100127698	XenbaseID:	XB-GENE-964846	Length:	324	Species:	Xenopus tropicalis

Alignment Length:	271	Identity:	99/271 - (36%)
Similarity:	143/271 - (52%)	Gaps:	20/271 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   525 ISAARSE-CGVPTLAR-PETRIVGGKSAAFGRWPWQVSVR--RTSFFGFSSTHRCGGALINENWI 585
            |.|..|| ||.|.|.. |.:|||||::|..|.||||||::  || ..|:|  |||||:||..||:
Frog    20 IQAIDSEVCGEPPLVHTPGSRIVGGRNALPGAWPWQVSLQYFRT-LSGYS--HRCGGSLIQNNWV 81

  Fly   586 ATAGHCVDDLLISQI-RIRVGEYDFSHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQP 649
            .:|.||.......:. |..:|.::.  ..|..|.::..:.:.::|..|..:....|:||:.|...
Frog    82 LSAAHCFRANRNPEYWRAVLGLHNI--FMEGSPVVKAKIKQIIIHASYDHIAITNDIALLLLHDF 144

  Fly   650 LEFAPHVSPICLPET---DSLLIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRA 711
            :.::.::.|:||...   |||..   ..:||||...|.|::..:|||..|..:....|.|.....
Frog   145 VTYSDYIHPVCLGSVTVPDSLTA---CFITGWGVTKEKGSISVILQEALVQTIPYSECNSSSSYN 206

  Fly   712 GRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQA-KSQDGRFFLAGIISWGIGCAEANLPGVCTRI 775
            |   ||....:|||..:|..||||||||||... .::..||:..||.|:|.||.:.|.|||.|::
Frog   207 G---FITQSMICAGDNSGAVDSCQGDSGGPFVCYNTERMRFYQMGITSFGYGCGKPNFPGVYTKV 268

  Fly   776 SKFTPWILEHV 786
            ..:..||..|:
Frog   269 ESYVSWIKAHM 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sb	NP_001287355.1	Tryp_SPc	543..782	CDD:214473	87/245 (36%)
Sb	NP_001287355.1	Tryp_SPc	544..785	CDD:238113	88/247 (36%)
tmprss12	XP_031751504.1	Tryp_SPc	41..278	CDD:238113	88/247 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910