Protein Alignment Akt and TPK2

DIOPT Version :10

• Sequence 1: NP_732113.3
• Gene: Akt / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_015121.1
• Gene: TPK2 / 855898
• SGDID: S000006124
• Length: 380
• Species: Saccharomyces cerevisiae
• Alignment Length: 297
• Identity: 127/297 - (42%)
• Similarity: 183/297 - (61%)
• Gaps: 4/297 - (1%)

  Fly   260 KVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHP 324
            |.||.:|:.::.||.|:||:|.|.|.....:.||||:|||:.:::..:|.||..|.|:||...||
Yeast    64 KYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHP 128

  Fly   325 FLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRD 389
            |||.:..:||....:..||.|:.|||||..|...:.|.....:||.||:|.||.|||:..|||||
Yeast   129 FLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRD 193

  Fly   390 LKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVM 454
            ||.||:|||::||||:.|||..||..|   .|.|.||||:|:||||:....|.::||||..||::
Yeast   194 LKPENILLDRNGHIKITDFGFAKEVQT---VTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLI 255

  Fly   455 YEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQA 519
            |||:.|..|||:......:..||..:|.:|.....:..:||:.|:..|..:|:|..:...::|:|
Yeast   256 YEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKA 320

  Fly   520 HPFFASINWTDLVLKKIPPPFKPQVTSDT-DTRYFDK 555
            ||:|:.:.|..|:.|.|..|::|.:||.. ||..||:
Yeast   321 HPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQ 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt	NP_732113.3	PH_PKB	105..214	CDD:269947
		STKc_PKB	270..590	CDD:270723	123/287 (43%)
TPK2	NP_015121.1	STKc_PKA_like	69..358	CDD:270732	124/292 (42%)