Protein Alignment Akt1 and YPK3

DIOPT Version :9

• Sequence 1: NP_732113.3
• Gene: Akt1 / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_009584.1
• Gene: YPK3 / 852316
• SGDID: S000000232
• Length: 525
• Species: Saccharomyces cerevisiae
• Alignment Length: 452
• Identity: 140/452 - (30%)
• Similarity: 211/452 - (46%)
• Gaps: 96/452 - (21%)

  Fly   203 TEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLENFE 267
            ::|:|..::||      ::||.      |:..:.|.|:|||.                 .|.:|:
Yeast    94 SDAMRTNTNRL------SITPQ------DIISSNIGENELSR-----------------NLHDFK 129

  Fly   268 FLKVLGKGTFGKVILCREKATAKLYAIKILKK-EVII--------QKDE---------------- 307
            .::|||:|.:|||:|.::..|:||||:|.|:| |::|        ::||
Yeast   130 PVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSK 194

  Fly   308 -VAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGA 371
             :..|..|..:|....||.::.|.|||..|.:|..::||:.|||||:||.......|....||.|
Yeast   195 RLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAA 259

  Fly   372 EIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK----------EDITYGRTTKTFCG 426
            ||..||.:||::|::|||||.||.||::.||:.:.||||.|          ||........:..|
Yeast   260 EISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIG 324

  Fly   427 TPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEE--VKFPRNITD 489
            ||||.|||:|....|.|..||:..|.::|:|:.|:.|:...:|.|:...|...:  .|.|..:::
Yeast   325 TPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSE 389

  Fly   490 EAKNLLAGLLAKDPKKR---------LGGGKDDVKE------------IQAHPFFASINWTDL-- 531
            ..|::|..||.|:..||         .|......|.            ...|..|..|:|..|
Yeast   390 GMKDILNALLKKETAKRWNVDKYWAKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKIDWKLLES 454

  Fly   532 --VLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPD--PTGPLGSIAEEP-LFPQFSYQ 588
              :.|....|..|.:|.......||.|||..|.|.|..|  |.. :.|:::.| :|..|||:
Yeast   455 GQLQKTTLGPIVPVITDLELAENFDTEFTSMSYEETYTDSKPIN-INSVSKSPDMFKGFSYK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt1	NP_732113.3	PH_PKB	105..214	CDD:269947	3/10 (30%)
		PH	107..211	CDD:278594	2/7 (29%)
		S_TKc	266..523	CDD:214567	103/315 (33%)
		STKc_PKB	270..590	CDD:270723	126/385 (33%)
YPK3	NP_009584.1	STKc_AGC	134..406	CDD:270693	96/271 (35%)
		S_TK_X	445..516	CDD:214529	23/72 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100157
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R469
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930