DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Akt1 and D6PKL1

DIOPT Version :9

Sequence 1:	NP_732113.3	Gene:	Akt1 / 41957	FlyBaseID:	FBgn0010379	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_194391.1	Gene:	D6PKL1 / 828768	AraportID:	AT4G26610	Length:	506	Species:	Arabidopsis thaliana

Alignment Length:	459	Identity:	124/459 - (27%)
Similarity:	195/459 - (42%)	Gaps:	128/459 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 GEVAMT-PSEQTDMTDVDMATIAEDELSEQFSVQGTTCNS-SGVKK------------------- 260
            |||... .|:|:..::....:.:.| :|::     :||:| ||..|
plant    57 GEVKFNEKSDQSGKSNTCRPSTSSD-ISDE-----STCSSFSGNNKPHKANDVRWEAIQAVRTKH 115

  Fly   261 --VTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNH 323
              :.|.:|..||.||.|..|.|.|.....|...:|:|::.|..:..:.::....||..:|:..:|
plant   116 GVLGLNHFRLLKRLGCGDIGTVHLAELHGTRCFFAMKVMDKGALASRKKLLRAQTEREILQCLDH 180

  Fly   324 PFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHER----IFTEDRTRFYGAEIISALGYLHSQG 384
            |||.:|...|:|....|.||::..||:|  |...:|    .|:|...:||.||::.|:.|||..|
plant   181 PFLPTLYSHFETEKFSCLVMEFCPGGDL--HTLRQRQPGKRFSEQAAKFYVAEVLLAMEYLHMLG 243

  Fly   385 IIYRDLKLENLLLDKDGHIKVADFGL---CKEDITYGRTT------------------------- 421
            |||||||.||:|:..|||:.::||.|   |....|..|:|
plant   244 IIYRDLKPENVLVRDDGHVMLSDFDLSLRCTVSPTVVRSTVLASEGQKNSGYCAQPACIQQPSCI 308

  Fly   422 ---------------------------------------------KTFCGTPEYLAPEVLDDNDY 441
                                                         .:|.||.||||||::....:
plant   309 SAPTTCFSPRYFSSKSKKDKKMKNETGNQVSPLPELVAEPTSARSMSFVGTHEYLAPEIIKGEGH 373

  Fly   442 GQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRN--ITDEAKNLLAGLLAKDPK 504
            |.|||||..|:.:||::.|:.||....:......::.:.::||.:  ::..|::|:..||.|:|:
plant   374 GSAVDWWTFGIFLYELLFGKTPFKGSGNRATLFNVVGQPLRFPESPVVSFAARDLIRSLLVKEPQ 438

  Fly   505 KRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPP-----------PFKPQVTSDTDTR-----YF 553
            .|| ..|....|::.||||..:||. ||....||           |..|...:.|..:     |.
plant   439 HRL-AYKRGATEMKQHPFFEGVNWA-LVRCASPPEIPKPVDYESAPATPAAATSTSVKSDQSNYL 501

  Fly   554 DKEF 557
            :.:|
plant   502 EFDF 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Akt1	NP_732113.3	PH_PKB	105..214	CDD:269947
		PH	107..211	CDD:278594
		S_TKc	266..523	CDD:214567	97/335 (29%)
		STKc_PKB	270..590	CDD:270723	108/383 (28%)
D6PKL1	NP_194391.1	STKc_phototropin_like	122..477	CDD:270726	105/358 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I1276
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960