DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Akt1 and WAG2

DIOPT Version :9

Sequence 1:	NP_732113.3	Gene:	Akt1 / 41957	FlyBaseID:	FBgn0010379	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_188054.1	Gene:	WAG2 / 820658	AraportID:	AT3G14370	Length:	480	Species:	Arabidopsis thaliana

Alignment Length:	454	Identity:	123/454 - (27%)
Similarity:	190/454 - (41%)	Gaps:	146/454 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 EQTDM----TDVDMA--------TIA------------EDELSEQFSVQGTTCNSSGVK------ 259
            ||.|.    ||:|::        |.|            .|.||...:|..::.:||.|.
plant     2 EQEDFYFPDTDLDLSFTSTTTDRTFASSSARTSLTLSFNDRLSTSSAVTTSSTSSSSVNHRRHDP 66

  Fly   260 ---------------KVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVA 309
                           .:.|.:.:.::.||.|..|:|.||..:.::..:|:|::.:..:..:.:::
plant    67 HWSAIKSAKLLSSDGNIHLRHLKLIRHLGTGNLGRVFLCNLRDSSARFALKVIDRNCLTTEKKLS 131

  Fly   310 HTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTE-------DRTR 367
            ...||:.:|...:||||.:|......:...|.::.|...|:|     |..:..:       ...|
plant   132 QVETEAEILSLLDHPFLPTLYARIDESHYTCLLIDYAPNGDL-----HSLLRKQPGNRLPIQPVR 191

  Fly   368 FYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLC-KEDIT-------YGRT---- 420
            |:.||::.||.|||:.||:|||||.||:||.:|||:.::||.|| |.|:.       |.|:
plant   192 FFAAEVLVALEYLHAMGIVYRDLKPENVLLREDGHVMLSDFDLCFKSDVVPTFKSRRYRRSSSSP 256

  Fly   421 -----------------------------------TKTFCGTPEYLAPEVLDDNDYGQAVDWWGT 450
                                               :::..||.||||||::..|.:|..||||..
plant   257 SLRRRRSGCFSVAAEKKYEREEIVSEFAAEPVTAFSRSCVGTHEYLAPELVSGNGHGSGVDWWAF 321

  Fly   451 GVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNIT--------------DEAKNLLAGLLAK 501
            |:.:||::.|..||.....:.  ||         |||.              |||::|:..||.|
plant   322 GIFLYELLYGTTPFKGESKEQ--TL---------RNIVSTTKTASFHMDGDLDEARDLIEKLLVK 375

  Fly   502 DPKKRLG--GGKDDVKEIQAHPFFASINW------------TDLVLKKIPPPFKPQVTSDTDTR 551
            ||:||||  .|..|:|.   ||||..|.|            ..||:||...|....|.:.:..|
plant   376 DPRKRLGCARGAQDIKR---HPFFDGIKWPLIRHYKPPEEVRGLVIKKSTRPHASHVIAVSPRR 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Akt1	NP_732113.3	PH_PKB	105..214	CDD:269947
		PH	107..211	CDD:278594
		S_TKc	266..523	CDD:214567	96/326 (29%)
		STKc_PKB	270..590	CDD:270723	107/364 (29%)
WAG2	NP_188054.1	STKc_phototropin_like	86..420	CDD:270726	102/352 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I1276
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960