DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Akt1 and PID2

DIOPT Version :9

Sequence 1:	NP_732113.3	Gene:	Akt1 / 41957	FlyBaseID:	FBgn0010379	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_180238.2	Gene:	PID2 / 817211	AraportID:	AT2G26700	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	415	Identity:	121/415 - (29%)
Similarity:	182/415 - (43%)	Gaps:	125/415 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 KKVTLENFEFLKVLGKGTFGKVILCREKATAK--LYAIKILKKEVIIQKDEVAHTLTESRVLKST 321
            :.|.||:|..||.||.|..|.|.||:.:.:.:  .||:|::.||.:..|.::.....|.::|...
plant    80 RAVGLEHFRLLKRLGSGDIGSVYLCQIRGSPETAFYAMKVVDKEAVAVKKKLGRAEMEKKILGML 144

  Fly   322 NHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHE--RIFTEDRTRFYGAEIISALGYLHSQG 384
            :|||..:|..:|:.:.....||:|..||:|:.....:  :.||...||||.||.:.||.|||..|
plant   145 DHPFCPTLYAAFEASHYSFLVMEYCPGGDLYAVRLRQPSKRFTISSTRFYAAETLVALEYLHMMG 209

  Fly   385 IIYRDLKLENLLLDKDGHIKVADFGL---C-------------------KEDI------------ 415
            |:|||||.||:|:.:|||:.::||.|   |                   .:||
plant   210 IVYRDLKPENVLIREDGHVMLSDFDLSFKCDVVPQFLSDNDRDRGHQEDDDDISIRRKCSTPSCT 274

  Fly   416 ----------------------------------------------TYGRT-------------- 420
                                                          |:.|:
plant   275 TTPLNPVISCFSPTSSRRRKKNVVTTTIHENAAGTSDSVKSNDVSRTFSRSPSSCSRVSNGLRDI 339

  Fly   421 ---------------TKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHD 470
                           :|:|.||.|||||||:....:|.|||||..|:.:||||.||.||...:::
plant   340 SGGCPSIFAEPINARSKSFVGTHEYLAPEVISGQGHGSAVDWWTYGIFLYEMIFGRTPFKGDNNE 404

  Fly   471 VLFTLILVEEVKFPRNITD---------EAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASI 526
            .....||...:.||:.|.:         .|::|:..||.|:||||||..|..: ||:.|.||..:
plant   405 KTLVNILKAPLTFPKVIVNSPKEYEDMVNAQDLIIKLLVKNPKKRLGSLKGSI-EIKRHEFFEGV 468

  Fly   527 NWTDLVLKKIPPPFKPQVTSDTDTR 551
            ||.  :::.|.||:.|:..:...|:
plant   469 NWA--LIRSIKPPWVPKEETSHKTK 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Akt1	NP_732113.3	PH_PKB	105..214	CDD:269947
		PH	107..211	CDD:278594
		S_TKc	266..523	CDD:214567	109/378 (29%)
		STKc_PKB	270..590	CDD:270723	116/404 (29%)
PID2	NP_180238.2	STKc_phototropin_like	86..483	CDD:270726	116/399 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I1276
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960