Protein Alignment Akt and aurkb

DIOPT Version :10

• Sequence 1: NP_732113.3
• Gene: Akt / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_997731.2
• Gene: aurkb / 791894
• ZFINID: ZDB-GENE-020419-40
• Length: 320
• Species: Danio rerio
• Alignment Length: 323
• Identity: 97/323 - (30%)
• Similarity: 162/323 - (50%)
• Gaps: 20/323 - (6%)

  Fly   218 EVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFGKVIL 282
            :|..|||.......|:|     :..:...|..|.....|..|.:::::|:..:.||||.||.|.|
Zfish    10 KVQQTPSAGVGPLRVEM-----NPDTHAVSGPGRVPVKSNSKVLSIDDFDIGRPLGKGKFGNVYL 69

  Fly   283 CREKATAKLYAIKILKKEVIIQKDEVAHTL-TESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYV 346
            .||:....:.|:|:|.|..:: |:.|.|.| .|..:.....||.::.....|..:.|:..:::|.
Zfish    70 ARERKLKVVIALKVLFKSQMV-KEGVEHQLRREIEIQSHLRHPNILRFYNYFHDDTRVFLILEYA 133

  Fly   347 NGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLC 411
            ..||::..|.....|.:.||..|..|:..||.|.|.:.:|:||:|.|||||...|.:|:||||..
Zfish   134 PRGEMYKELQRYGHFDDQRTATYMEEVSDALQYCHEKKVIHRDIKPENLLLGYRGELKIADFGWS 198

  Fly   412 KEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLI 476
            ....:..|  :|.|||.:||.||:::.:.:.:.||.|..||:.||.:.|..||....|...:..|
Zfish   199 VHAPSLRR--RTMCGTLDYLPPEMIEGHSHDEKVDLWSIGVLCYECLVGNPPFETASHAETYKRI 261

  Fly   477 LVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPP 539
            ...:::||:.:::.|::|::.||...|..||     .::.:..||      |.....:::.||
Zfish   262 TKVDLQFPKLVSEGARDLISKLLRHSPSMRL-----PLRSVMEHP------WVKANSRRVLPP 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt	NP_732113.3	PH_PKB	105..214	CDD:269947
		STKc_PKB	270..590	CDD:270723	86/271 (32%)
aurkb	NP_997731.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		7/32 (22%)
		STKc_Aurora-B_like	46..315	CDD:271019	88/282 (31%)