Protein Alignment Akt and Stk38l

DIOPT Version :10

• Sequence 1: NP_732113.3
• Gene: Akt / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001076805.1
• Gene: Stk38l / 691337
• RGDID: 1564793
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 436
• Identity: 131/436 - (30%)
• Similarity: 218/436 - (50%)
• Gaps: 69/436 - (15%)

  Fly   190 TFAVESELERQQWTEA---IRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGT 251
            ||.:.|. .|::.|.|   :.|..|.||...|     ..:|....:::|...|....|:..::
  Rat    10 TFPMSSH-TRERVTVAKLTLENFYSNLILQHE-----ERETRQKKLEVAMEEEGLADEEKKLR-- 66

  Fly   252 TCNSSGVKKVT-----------LENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQK 305
              .|...:|.|           |::||.|||:|:|.||:|.|.::|.|..:||:|||:|..:::|
  Rat    67 --RSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEK 129

  Fly   306 DEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYG 370
            ::|||...|..:|...:..:::.:.||||....|..:|:::.||::...|..:...||:.|:||.
  Rat   130 EQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYI 194

  Fly   371 AEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK-----------EDITYG------ 418
            :|.:.|:..:|..|.|:||:|.:|||||..||:|::|||||.           .::|:.
  Rat   195 SETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFS 259

  Fly   419 -------RTTKTF-----------CGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFY 465
                   |..:|:           .|||:|:||||.....|.:..|||..||:||||:.|..||.
  Rat   260 FQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGFPPFC 324

  Fly   466 NRDHDVLFTLIL--VEEVKFPRN--ITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASI 526
            :......:..::  .|.:.||..  ::::||:|:. ....|.:.|:|.|  .|:||:.||||..:
  Rat   325 SETPQETYRKVMSWKETLAFPPEVPVSEKAKDLIL-RFCTDSENRIGNG--GVEEIKGHPFFEGV 386

  Fly   527 NWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPDPTGP 572
            :|..  :::.|.....::.|..||..|| :|....:....|:.|.|
  Rat   387 DWGH--IRERPAAIPIEIRSIDDTSNFD-DFPESDILQPVPNTTEP 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt	NP_732113.3	PH_PKB	105..214	CDD:269947	8/26 (31%)
		STKc_PKB	270..590	CDD:270723	109/342 (32%)
Stk38l	NP_001076805.1	MobB_NDR_LATS-like	12..86	CDD:459252	16/83 (19%)
		STKc_NDR2	87..452	CDD:270776	113/349 (32%)