| Sequence 1: | NP_732113.3 | Gene: | Akt1 / 41957 | FlyBaseID: | FBgn0010379 | Length: | 611 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002731.4 | Gene: | PRKCI / 5584 | HGNCID: | 9404 | Length: | 596 | Species: | Homo sapiens |
| Alignment Length: | 366 | Identity: | 155/366 - (42%) |
|---|---|---|---|
| Similarity: | 233/366 - (63%) | Gaps: | 20/366 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 223 PSEQTDMTDVDMATI---------AEDELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFG 278
Fly 279 KVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVL-KSTNHPFLISLKYSFQTNDRLCFV 342
Fly 343 MQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVAD 407
Fly 408 FGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPF------YN 466
Fly 467 RD---HDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLG-GGKDDVKEIQAHPFFASIN 527
Fly 528 WTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPD 568 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Akt1 | NP_732113.3 | PH_PKB | 105..214 | CDD:269947 | |
| PH | 107..211 | CDD:278594 | |||
| S_TKc | 266..523 | CDD:214567 | 128/267 (48%) | ||
| STKc_PKB | 270..590 | CDD:270723 | 145/310 (47%) | ||
| PRKCI | NP_002731.4 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..23 | ||
| Regulatory domain | 2..253 | 8/50 (16%) | |||
| Required for interaction with RAB2 | 2..28 | ||||
| PB1_aPKC | 26..108 | CDD:99725 | |||
| Interaction with PARD6A | 72..91 | ||||
| Pseudosubstrate. /evidence=ECO:0000250 | 125..134 | ||||
| C1_1 | 141..191 | CDD:365894 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 220..246 | 3/25 (12%) | |||
| STKc_aPKC_iota | 233..596 | CDD:270769 | 149/335 (44%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D614710at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.920 | |||||