Protein Alignment Akt and Pka-C2

DIOPT Version :10

• Sequence 1: NP_732113.3
• Gene: Akt / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_733397.2
• Gene: Pka-C2 / 43644
• FlyBaseID: FBgn0000274
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 321
• Identity: 123/321 - (38%)
• Similarity: 188/321 - (58%)
• Gaps: 8/321 - (2%)

  Fly   240 DELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQ 304
            |.:|.:|..:......|  ....|||:....|||.|:||.|:|.|||:....||.|::.||.:::
  Fly    21 DNMSREFEERWNHQTQS--PYTNLENYITRAVLGNGSFGTVMLVREKSGKNYYAAKMMSKEDLVR 83

  Fly   305 KDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFY 369
            ..:|||...|..||.:...||||.|..|.:..|.|..::..|||||||.:....|.|.|...|||
  Fly    84 LKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFSYHRRVRKFNEKHARFY 148

  Fly   370 GAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPE 434
            .|::..||.|:|...::|||||.||:|||:.|:||:.|||..|.  ..|||: |.||||||||||
  Fly   149 AAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKR--VDGRTS-TLCGTPEYLAPE 210

  Fly   435 VLDDNDYGQAVDWWGTGVVMYEMICGRLPF--YNRDHDVLFTLILVEEVKFPRNITDEAKNLLAG 497
            ::....|.::||||..|:::||.:.||.||  :|||..::::.|.:.:.|.|...|.:.::|:..
  Fly   211 IVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKICICDYKMPSYFTSQLRSLVES 275

  Fly   498 LLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDK-EF 557
            |:..|..||||...|...::::||:|..::|..::.:::..|::|.::...|...|:. ||
  Fly   276 LMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTISGAEDLSNFENFEF 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt	NP_732113.3	PH_PKB	105..214	CDD:269947
		STKc_PKB	270..590	CDD:270723	116/291 (40%)
Pka-C2	NP_733397.2	Protein Kinases, catalytic domain	43..334	CDD:473864	116/293 (40%)