DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Akt1 and Stk32b

DIOPT Version :9

Sequence 1:	NP_732113.3	Gene:	Akt1 / 41957	FlyBaseID:	FBgn0010379	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_001100694.1	Gene:	Stk32b / 305431	RGDID:	1306173	Length:	414	Species:	Rattus norvegicus

Alignment Length:	295	Identity:	98/295 - (33%)
Similarity:	161/295 - (54%)	Gaps:	19/295 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   259 KKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNH 323
            ::|..::|:.|:.:|||:||||.:.:::.|.|:||:|.:.|:..:::|||.:...|.::::...|
  Rat    16 EEVNFDHFQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQKCVERDEVRNVFRELQIMQGLEH 80

  Fly   324 PFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYR 388
            |||::|.||||..:.:..|:..:.||:|.:||.....|||...:.|..|:..||.||....||:|
  Rat    81 PFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEGAVKLYVCELALALEYLQRYHIIHR 145

  Fly   389 DLKLENLLLDKDGHIKVADFGLCKEDITYG-RTTKTFCGTPEYLAPEVLD-----DNDYGQAVDW 447
            |:|.:|:|||:.||:.:.||.:.  .:..| ....:..||..|:|||:..     ...|...|||
  Rat   146 DIKPDNILLDEHGHVHITDFNIA--TVLKGTEKASSMAGTKPYMAPEIFQVYVDGGPGYSYPVDW 208

  Fly   448 WGTGVVMYEMICGRLPFYNRDH-----DVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRL 507
            |..||..||::.|..|:  ..|     |.:..:..||.|.:.....:...:||..||.|||:.||
  Rat   209 WSLGVTAYELLRGWRPY--EIHSATPVDEILNMFKVERVHYSSTWCEGMVDLLKKLLTKDPEIRL 271

  Fly   508 GGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKP 542
                ..:::||:..:.|.:||..:..|.:.|.|.|
  Rat   272 ----SSLRDIQSMTYLADMNWDAVFNKALMPGFVP 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Akt1	NP_732113.3	PH_PKB	105..214	CDD:269947
		PH	107..211	CDD:278594
		S_TKc	266..523	CDD:214567	90/267 (34%)
		STKc_PKB	270..590	CDD:270723	95/284 (33%)
Stk32b	NP_001100694.1	STKc_Yank1	22..283	CDD:270730	90/268 (34%)
Stk32b	NP_001100694.1	S_TKc	23..272	CDD:214567	88/256 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910