Protein Alignment Akt1 and Prkca

DIOPT Version :9

• Sequence 1: NP_732113.3
• Gene: Akt1 / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_038941139.1
• Gene: Prkca / 24680
• RGDID: 3395
• Length: 722
• Species: Rattus norvegicus
• Alignment Length: 491
• Identity: 185/491 - (37%)
• Similarity: 261/491 - (53%)
• Gaps: 89/491 - (18%)

  Fly   182 QWTTVIERTFAVE-SELERQ------QWTEAIRN--VSSRLIDVGEVAMTPS---------EQTD 228
            ||....  ||.:: |:.:|:      .|....||  :.|....|.|:...|:         |:.:
  Rat   222 QWNESF--TFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGE 284

  Fly   229 MTDVDMATIAED---ELSEQF--SVQGTTCN------------SSGVKKVTLENFEFLKVLGKGT 276
            ..:|.:....|:   ||.::|  :..|...|            |:.:.:|.|.:|.||.|||||:
  Rat   285 YYNVPIPEGDEEGNVELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGS 349

  Fly   277 FGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNH-PFLISLKYSFQTNDRLC 340
            ||||:|...|.|.:|||||||||:|:||.|:|..|:.|.|||...:. |||..|...|||.|||.
  Rat   350 FGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLY 414

  Fly   341 FVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKV 405
            |||:|||||:|.:|:.....|.|.:..||.|||...|.:||.:|||||||||:|::||.:||||:
  Rat   415 FVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKI 479

  Fly   406 ADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHD 470
            ||||:|||.:..|.||:||||||:|:|||::....||::||||..||::|||:.|:.||...|.|
  Rat   480 ADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDED 544

  Fly   471 VLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKK 535
            .||..|:...|.:|::::.||.::..||:.|.|.||||.|.:..::::.|.||..|:|..|..::
  Rat   545 ELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENRE 609

  Fly   536 IPPPFKPQVTSDTDTR------------------------------------------------- 551
            |.|||||:|....:.|
  Rat   610 IQPPFKPKVQCTAEVRGFTAFSTQLFLILDISNSSPLSVLILQNFCTKMHWLQWASRPSCGKGAE 674

  Fly   552 YFDKEFTGESVELTPPDPTGPLGSIAEEPLFPQFSY 587
            .|||.||.....|||||.. .:.:| ::..|..|||
  Rat   675 NFDKFFTRGQPVLTPPDQL-VIANI-DQSDFEGFSY 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt1	NP_732113.3	PH_PKB	105..214	CDD:269947	10/40 (25%)
		PH	107..211	CDD:278594	9/37 (24%)
		S_TKc	266..523	CDD:214567	133/257 (52%)
		STKc_PKB	270..590	CDD:270723	158/368 (43%)
Prkca	XP_038941139.1	C1_cPKC_rpt1	35..92	CDD:410383
		C1_cPKC_rpt2	102..155	CDD:410386
		C2_PKC_alpha_gamma	159..289	CDD:175992	14/68 (21%)
		PKc_like	328..718	CDD:419665	164/383 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614710at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920