Protein Alignment Akt1 and Sgk1

DIOPT Version :9

• Sequence 1: NP_732113.3
• Gene: Akt1 / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001155317.2
• Gene: Sgk1 / 20393
• MGIID: 1340062
• Length: 524
• Species: Mus musculus
• Alignment Length: 457
• Identity: 202/457 - (44%)
• Similarity: 266/457 - (58%)
• Gaps: 46/457 - (10%)

  Fly   162 GCQIM-------TVDRPKPFTFIIRGLQWTTVIERTFAVESELERQQWTEAIRNVSSRLIDVGEV 219
            ||::.       .:.:|.|.||      ||    ...|...:..|....:.|:.::|     ...
Mouse    91 GCEVKEQCNHANILTKPDPRTF------WT----NDDAAFMKQRRMGLNDFIQKIAS-----NTY 140

  Fly   220 AMTPSEQTDMTDVDMATIAEDEL-----------SEQFSVQGTTCNSSGVKKVTLENFEFLKVLG 273
            |...:|...:  :.|:...|.||           |:|.:: |.:.|.....    .:|.||||:|
Mouse   141 ACKHAEVQSI--LKMSHPQEPELMNANPSPPPSPSQQINL-GPSSNPHAKP----SDFHFLKVIG 198

  Fly   274 KGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRV-LKSTNHPFLISLKYSFQTND 337
            ||:||||:|.|.||....||:|:|:|:.|::|.|..|.::|..| ||:..||||:.|.:||||.|
Mouse   199 KGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTAD 263

  Fly   338 RLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGH 402
            :|.||:.|:||||||:||..||.|.|.|.|||.|||.||||||||..|:|||||.||:|||..||
Mouse   264 KLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGH 328

  Fly   403 IKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNR 467
            |.:.|||||||:|.:..||.||||||||||||||....|.:.||||..|.|:|||:.|..|||:|
Mouse   329 IVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSR 393

  Fly   468 DHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLV 532
            :...::..||.:.::...|||:.|::||.|||.||..||| |.|||..||::|.||:.|||.||:
Mouse   394 NTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRL-GAKDDFMEIKSHIFFSLINWDDLI 457

  Fly   533 LKKIPPPFKPQVTSDTDTRYFDKEFTGESVELT---PPDPTGPLGSIAE-EPLFPQFSYQGDMAS 593
            .|||.|||.|.|:..:|.|:||.|||.|.|..:   .||......|:.| ...|..|||...:.|
Mouse   458 NKKITPPFNPNVSGPSDLRHFDPEFTEEPVPSSIGRSPDSILVTASVKEAAEAFLGFSYAPPVDS 522

  Fly   594 TL 595
            .|
Mouse   523 FL 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt1	NP_732113.3	PH_PKB	105..214	CDD:269947	12/58 (21%)
		PH	107..211	CDD:278594	11/55 (20%)
		S_TKc	266..523	CDD:214567	146/257 (57%)
		STKc_PKB	270..590	CDD:270723	175/324 (54%)
Sgk1	NP_001155317.2	STKc_SGK1	183..521	CDD:270753	179/342 (52%)
		S_TKc	191..448	CDD:214567	146/257 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614710at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100157
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R469
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850