DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Akt1 and stk32a

DIOPT Version :9

Sequence 1:	NP_732113.3	Gene:	Akt1 / 41957	FlyBaseID:	FBgn0010379	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	XP_002936753.2	Gene:	stk32a / 100490429	XenbaseID:	XB-GENE-490728	Length:	398	Species:	Xenopus tropicalis

Alignment Length:	296	Identity:	99/296 - (33%)
Similarity:	167/296 - (56%)	Gaps:	13/296 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 CNSSGVKKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRV 317
            |:.:  ::|...:||.|:.:|||:||||.:.::..|.|:||:|.:.|:..::::||.:...|.::
Frog    12 CDEN--EEVNFNHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQI 74

  Fly   318 LKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHS 382
            ::...||||::|.||||..:.:..|:..:.||:|.:||.....|||...:.|..|:..||.||.|
Frog    75 MQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVRFTEASVKLYICELALALDYLQS 139

  Fly   383 QGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDND---YGQA 444
            :.||:||:|.:|:|||:.||:.:.||.:... ::.|....|..||..|:|||:.....   |...
Frog   140 KSIIHRDIKPDNVLLDEQGHVHITDFNIATL-VSKGTKITTVAGTKPYMAPEMFYPRGQICYSFG 203

  Fly   445 VDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILV---EEVKFPRNITDEAKNLLAGLLAKDPKKR 506
            ||||..||..||::.||.||:.........::.|   ..|.:|...::|..:||..||.::|::|
Frog   204 VDWWSLGVTAYELLRGRRPFHIHSSTAATDIVHVFHTATVTYPPAWSEEIVSLLHKLLDRNPEER 268

  Fly   507 LGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKP 542
            .    ..::.||..|:.:.:||...:.|::.|.|.|
Frog   269 F----SCLEHIQDFPYLSDVNWDAALQKRLSPQFIP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Akt1	NP_732113.3	PH_PKB	105..214	CDD:269947
		PH	107..211	CDD:278594
		S_TKc	266..523	CDD:214567	91/262 (35%)
		STKc_PKB	270..590	CDD:270723	94/279 (34%)
stk32a	XP_002936753.2	STKc_Yank1	22..281	CDD:270730	91/263 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000