Protein Alignment Akt and prkcdb

DIOPT Version :10

• Sequence 1: NP_732113.3
• Gene: Akt / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001352166.1
• Gene: prkcdb / 100150844
• ZFINID: ZDB-GENE-111129-1
• Length: 685
• Species: Danio rerio
• Alignment Length: 329
• Identity: 155/329 - (47%)
• Similarity: 213/329 - (64%)
• Gaps: 7/329 - (2%)

  Fly   260 KVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLK-STNH 323
            :|:|.:|.|.||||||:||||:|...|...:.:|||.|||:|::..|:|..|:.|.|||. :..:
Zfish   352 RVSLNDFVFQKVLGKGSFGKVMLAELKGKGQYFAIKALKKDVVLMDDDVECTMVEKRVLALAWEN 416

  Fly   324 PFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYR 388
            |||..|..:||:.:.|.|||:|:|||:|.:|:..:..|...|..||.||||..|.||||:||:||
Zfish   417 PFLTHLYCTFQSKEHLFFVMEYLNGGDLMFHIQDKGRFDLYRATFYAAEIICGLQYLHSKGIVYR 481

  Fly   389 DLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVV 453
            ||||:|::||||||||:||||:|||::.......||||||:|:|||:|....|..:||||..||:
Zfish   482 DLKLDNVMLDKDGHIKIADFGMCKENMIGENRATTFCGTPDYIAPEILLGQKYSFSVDWWSFGVL 546

  Fly   454 MYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQ 518
            :|||:.|:.||...|.|.||..|.::...:||.||.|||:||..|..:||.:|||    .|..|:
Zfish   547 LYEMLIGQSPFQGDDEDELFDSIRMDVPHYPRWITKEAKDLLEKLFERDPTRRLG----VVGNIR 607

  Fly   519 AHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPDPTGPLGSIAEEPLFP 583
            .|.||.:|||..|..:::.|||||:|.|.:|...||:||..|...|:..|..  |....::..|.
Zfish   608 GHAFFKTINWPALEKREVSPPFKPKVKSSSDCSNFDREFLSEKPRLSQSDKN--LIDSMDQTAFA 670

  Fly   584 QFSY 587
            .||:
Zfish   671 GFSF 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt	NP_732113.3	PH_PKB	105..214	CDD:269947
		STKc_PKB	270..590	CDD:270723	151/319 (47%)
prkcdb	NP_001352166.1	C1_nPKC_theta-like_rpt1	153..213	CDD:410384
		C1_nPKC_theta-like_rpt2	232..281	CDD:410387
		Protein Kinases, catalytic domain	362..677	CDD:473864	151/319 (47%)