Protein Alignment Akt and prkcq

DIOPT Version :10

• Sequence 1: NP_732113.3
• Gene: Akt / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_012813823.2
• Gene: prkcq / 100038268
• XenbaseID: XB-GENE-487643
• Length: 699
• Species: Xenopus tropicalis
• Alignment Length: 558
• Identity: 188/558 - (33%)
• Similarity: 286/558 - (51%)
• Gaps: 58/558 - (10%)

  Fly    53 PTSGS-AEKFSW---QQSWPSRTSAAPTHDSGTMSINTTFDLSSPSVTSGHALTEQTQVVKEGWL 113
            ||..| ..:|.|   :|.:..|...|..|       ....|......|.....:::|.:.||.:.
 Frog   167 PTFCSVCHEFVWGLNKQGYQCRQCNAAIH-------KKCIDKVIAKCTGSAVNSKETVLHKERFK 224

  Fly   114 MKRGEHIK--NWRQRYFVLHSDGRLMGYRSKPADSASTPSDFLLNNFTV-RGCQIMTVDRPKPFT 175
            :......|  |:|...|..|....|.|...:....|..       |..| ..|.:...:
 Frog   225 IDMPHRFKVNNYRSPTFCEHCGTLLWGLARQGLKCAEC-------NMNVHHKCAVKVAN------ 276

  Fly   176 FIIRGLQWTTVIERTFAVESELE--RQQWTEAIRNVSSRLIDVGEVAMTPSEQTDM--------- 229
              :.|:....:.|....:|:..:  ||:.:|.|.....  ::||....|..:...:
 Frog   277 --LCGVNQKLMAEALAMIETTQQDRRQRDSEFIYREGP--VNVGPTTNTQDQPIVLSIKKESQGI 337

  Fly   230 ---TDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFGKVILCREKATAKL 291
               :.::...:.|.....:..::.::|..    |||..:|...|:||||:||||.|...|.|.:.
 Frog   338 SWESPIESIKVQESPPEPELKIEQSSCQI----KVTFSDFVLHKMLGKGSFGKVFLAELKRTNQF 398

  Fly   292 YAIKILKKEVIIQKDEVAHTLTESRVLK-STNHPFLISLKYSFQTNDRLCFVMQYVNGGELFWHL 355
            :|||:|||:|::..|:|..|:.|.|||. :..||||..|..:|||.:.|.|||:|:|||:|.:|:
 Frog   399 FAIKVLKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHLYCTFQTKEHLFFVMEYLNGGDLMFHI 463

  Fly   356 SHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRT 420
            .....|...|..||.|||:..|.:|||:|::||||||:|:|||.:||||:||||:|||.:.....
 Frog   464 QSCHKFDLPRATFYAAEIVCGLQFLHSKGVVYRDLKLDNILLDMEGHIKIADFGMCKESMLGDAK 528

  Fly   421 TKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPR 485
            |.||||||:|:|||:|....|..:||||..||::|||:.|:.||:..|.:.||..|.::...:||
 Frog   529 TSTFCGTPDYIAPEILLGQKYNYSVDWWSFGVLLYEMLIGQSPFHGIDEEELFQSIRMDNPMYPR 593

  Fly   486 NITDEAKNLLAGLLAKDPKKRLGGGKDDVK-EIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTD 549
            .::.|||::|..|..::|::|||     || :|:.|.||..|:|..|..::|.|||||:|.|..|
 Frog   594 FLSMEAKDILIMLFVREPERRLG-----VKGDIRQHCFFQHIDWGRLENREIEPPFKPKVKSADD 653

  Fly   550 TRYFDKEFTGESVELTPPDPTGPLGSIAEEPLFPQFSY 587
            ...|||||..|...|:..:.|  |.:..::.:|..||:
 Frog   654 WSNFDKEFLNEKPRLSSSERT--LINSMDQNMFNNFSF 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt	NP_732113.3	PH_PKB	105..214	CDD:269947	21/113 (19%)
		STKc_PKB	270..590	CDD:270723	147/320 (46%)
prkcq	XP_012813823.2	C1_nPKC_theta-like_rpt1	150..210	CDD:410384	11/49 (22%)
		C1_nPKC_theta-like_rpt2	229..278	CDD:410387	11/63 (17%)
		STKc_nPKC_theta	367..697	CDD:270770	151/330 (46%)