Protein Alignment Akt1 and prkcg

DIOPT Version :9

• Sequence 1: NP_732113.3
• Gene: Akt1 / 41957
• FlyBaseID: FBgn0010379
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_001921715.1
• Gene: prkcg / 100003514
• ZFINID: ZDB-GENE-090206-1
• Length: 695
• Species: Danio rerio
• Alignment Length: 565
• Identity: 206/565 - (36%)
• Similarity: 295/565 - (52%)
• Gaps: 97/565 - (17%)

  Fly    82 MSINTTFDLSSPSVTSGHALTEQTQVVKEGWLMKRGEHIKNWRQRYFVLHSDGRLMGYRSKPADS 146
            |:::...:.|.||: .|...||:...::   |..|||.    ...|..:|....|:     |.|.
Zfish   156 MNVHKRCESSVPSL-CGQDHTEKRGRIR---LTVRGEK----EDIYITVHEALNLI-----PMDP 207

  Fly   147 ASTPSDFLLNNFTVRGCQIMTVDRPK--------------------PFTFIIRGLQWTTVIERTF 191
            ......::         ::..:..||                    .|||.:||.||    :|..
Zfish   208 NGLSDPYV---------KLKLIPDPKSHSKQKTKTIRSTLNPIWNESFTFSVRGRQW----DRRL 259

  Fly   192 AVE----SELERQQWTEAI---------RNVSS--RLI--DVGE--------------------- 218
            :||    ....|..:..|:         |:||.  :|:  |.||
Zfish   260 SVEVWDWDRTSRNDFMGALSFGVSEIFRRSVSGWFKLLNQDEGEYYNIPVPDPDLQVPEEILMPS 324

  Fly   219 VAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTCNSSGVKKVTLENFEFLKVLGKGTFGKVILC 283
            :..|||..|    ..:..:....||...:|..|     |...:.|.:|.||.|||||:||||:|.
Zfish   325 IPPTPSPVT----TPVPAVTPPALSPAPAVLHT-----GKGHIGLHDFNFLMVLGKGSFGKVLLA 380

  Fly   284 REKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHP-FLISLKYSFQTNDRLCFVMQYVN 347
            .||.:.:|:|||:|||:|:.|.::....:.|.|||..:..| ||.||..:|||.|||.:||:|||
Zfish   381 EEKGSERLFAIKMLKKDVLFQDEDTESAMVERRVLALSGRPHFLTSLYCAFQTEDRLYYVMEYVN 445

  Fly   348 GGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCK 412
            ||:|.:|:.....|.|....||.|||...|.:||::|||||||||:|:|||.:||||:||||:|:
Zfish   446 GGDLMFHIQIVGKFKEPHAAFYAAEIAVGLFFLHNKGIIYRDLKLDNVLLDSEGHIKIADFGMCR 510

  Fly   413 EDITYGRTTKTFCGTPEYLAPEVLDDNDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLIL 477
            |.:..|.||:||||||:|:|||::....||:|||||..||::|||:.|:.||...|.:.||..|:
Zfish   511 EGMMEGDTTRTFCGTPDYIAPEIVAYQPYGKAVDWWSYGVLLYEMLAGQPPFDGIDEEELFQSIM 575

  Fly   478 VEEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKP 542
            .:.|.:|::::.||..:..|||.|:|.||||||:|..:|::.||||..|:|..|...:|.|||||
Zfish   576 EQSVSYPKSLSREAVAICKGLLTKNPAKRLGGGEDAERELREHPFFRWIDWDRLERLEIQPPFKP 640

  Fly   543 QVTSDTDTRYFDKEFTGESVELTPPDPTGPLGSIAEEPLFPQFSY 587
            : :.......|||.||..|..|||.|| ..|.:|.:|. |..|::
Zfish   641 R-SGGKKGENFDKFFTSTSSALTPSDP-DVLAAINQEE-FQDFTF 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Akt1	NP_732113.3	PH_PKB	105..214	CDD:269947	26/143 (18%)
		PH	107..211	CDD:278594	25/136 (18%)
		S_TKc	266..523	CDD:214567	132/257 (51%)
		STKc_PKB	270..590	CDD:270723	156/319 (49%)
prkcg	XP_001921715.1	C1_1	56..108	CDD:278556
		C1_1	121..173	CDD:278556	5/17 (29%)
		C2_PKC_alpha_gamma	178..308	CDD:175992	30/154 (19%)
		S_TKc	363..621	CDD:214567	132/257 (51%)
		STKc_cPKC	366..684	CDD:270739	157/320 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614710at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920