DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mhcl and si:dkey-276j7.2

DIOPT Version :9

Sequence 1:	NP_732109.2	Gene:	Mhcl / 41955	FlyBaseID:	FBgn0026059	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	XP_017212076.1	Gene:	si:dkey-276j7.2 / 792667	ZFINID:	ZDB-GENE-131127-420	Length:	250	Species:	Danio rerio

Alignment Length:	144	Identity:	32/144 - (22%)
Similarity:	64/144 - (44%)	Gaps:	29/144 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   336 RQLVIRRQKSPRQDFGFSLRKAICLDRTESLT-----SPIFRPVIFAEPGAGGGATGLLPGDRLI 395
            |::|..:.|:..|    .:||::.|.|||:.|     ..:...|.|.:..:...::||:..|.:|
Zfish    57 RKVVQTQDKTAEQ----CIRKSVILRRTENETFGFEIQDLVPCVCFVKEDSLAESSGLMTDDVII 117

  Fly   396 KVNGTPVGELPRE-----------IIIEMIRNSGEAVTVEVQPVAELV----ELSKRCMAPSTAT 445
            .||...:.|..::           :::|::|:|.|.   :.|.:..|.    |.:::.....|..
Zfish   118 AVNSVSIAEFTQQQLKDLFQKASILMLEIVRSSTEK---QRQLLIRLYLLQREFAEKSAELQTLN 179

  Fly   446 VEEIDHSITNGNCN 459
            .||:  .:..|.|:
Zfish   180 TEEV--RLIGGVCS 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492	23/102 (23%)
		MYSc	556..1317	CDD:214580
		MYSc_Myo18	575..1305	CDD:276837
		GBP_C	<1540..1750	CDD:303769
		COG1340	1565..1833	CDD:224259
		coiled coil	1723..1734	CDD:293879
si:dkey-276j7.2	XP_017212076.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900