Protein Alignment Mhcl and pdzd3a

DIOPT Version :9

• Sequence 1: NP_732109.2
• Gene: Mhcl / 41955
• FlyBaseID: FBgn0026059
• Length: 2194
• Species: Drosophila melanogaster
• Sequence 2: XP_685398.3
• Gene: pdzd3a / 557269
• ZFINID: ZDB-GENE-080430-1
• Length: 520
• Species: Danio rerio
• Alignment Length: 535
• Identity: 108/535 - (20%)
• Similarity: 171/535 - (31%)
• Gaps: 186/535 - (34%)

  Fly   270 HLHVLTSPS--PSADSLTDTTNSSFATP----PFSLSPVGESQGIDRWARVHAFEDVELPLPPVQ 328
            ||:|..:||  |....:...|..:...|    .|:.:|   .:|||..|.|.: :|.|   |.|.
Zfish     3 HLNVYLAPSQHPGLRRIMRFTAETVEAPDLPKKFTFNP---KEGIDNPALVIS-DDKE---PDVH 60

  Fly   329 LVKLPPPRQLVIRRQKSPRQDFGFSLRK------------------------------------- 356
                  ||..|:||::.  |.|||.|.:
Zfish    61 ------PRLCVLRREEG--QGFGFYLSRDAGRCRGHVVRQVEPWSSAERAGLRIGDHVLEVNEDF 117

  Fly   357 --------------------------------AICLDRTESLTSPIFRPV---------IFAEPG 380
                                            |:...|.....:..:||.         |..|||
Zfish   118 VDDKEHSTVVLKVQASGLKLYLLVLSAQDYEFAVSEGRDLLSVARSYRPEGCSRPRLCHITKEPG 182

  Fly   381 AGGGAT------------------------GLLPGDRLIKVNGTPVGELPREIIIEMIRNSGEAV 421
            .|.|.:                        |:..|||||.:||..:..:....:.:|::...:.:
Zfish   183 CGLGLSIIPIEGARGRYRLNPVTDGPAERAGIQNGDRLIWINGVSISVISYAALAKMVKKCEKHL 247

  Fly   422 TVEVQPVAELVELSKRC---MAPSTATVEEIDH-----SITNGNCN---TLRRS--ASKRFKRQS 473
            ||.|.. :...|:..|.   :.|:.|....:.:     .:|.|...   .||:.  .|.|.....
Zfish   248 TVLVID-SRSEEIYNRMGLPIIPAFAETHNLPYRPKTLHLTQGPQGYGFLLRQEKLRSGRIAHIL 311

  Fly   474 RHENGNGGGEEGGAKGVGHDLEADVADASQPERVWLVHRGGFTAAIR-------LPTAS-SGRDE 530
            |..:.....|..|.:      :.::..|...|:|......|..:.||       |.|.| :|||.
Zfish   312 REIDPCSPAETAGME------DGEIVLAVNGEQVEDAEHEGIVSKIRQSGQQVTLTTISIAGRDF 370

  Fly   531 ENKLSLRLLHNGEQLTVDE--DDVEKQNSPALDLVED--------ICELKYLNEAS----VLHCL 581
            ..:|::..|     |..||  ...|...:|||:..|.        :|||.  .|.:    .|.|:
Zfish   371 YTQLAMSPL-----LFYDEHIPKCEPFATPALEHPEGHQNPPQPRLCELH--KEGTGFGFNLGCV 428

  Fly   582 RQRYASNLIHTKAGPT-----------LLVVNPMAPLSLYSEKVVSMFRGCKTEDMPPHVYSLAQ 635
            ..:..:.:....:|.|           |:.||.......|.::||.:..|..|   |..:..:..
Zfish   429 ENKPGTYIGQVVSGSTGERAGLRKWDVLIEVNGQNVEDEYFDEVVRLITGGGT---PLRLLVVDG 490

  Fly   636 TAYRSLVETRRDQSL 650
            ..|..|..||:..:|
Zfish   491 LQYDKLRNTRQTINL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492	29/188 (15%)
		MYSc	556..1317	CDD:214580	26/118 (22%)
		MYSc_Myo18	575..1305	CDD:276837	18/91 (20%)
		GBP_C	<1540..1750	CDD:303769
		COG1340	1565..1833	CDD:224259
		coiled coil	1723..1734	CDD:293879
pdzd3a	XP_685398.3	PDZ_signaling	61..142	CDD:238492	10/82 (12%)
		PDZ_signaling	172..252	CDD:238492	17/79 (22%)
		PDZ	280..363	CDD:214570	16/88 (18%)
		PDZ	408..490	CDD:214570	17/86 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900