DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mhcl and PDZD11

DIOPT Version :9

Sequence 1:	NP_732109.2	Gene:	Mhcl / 41955	FlyBaseID:	FBgn0026059	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	XP_016885057.1	Gene:	PDZD11 / 51248	HGNCID:	28034	Length:	172	Species:	Homo sapiens

Alignment Length:	148	Identity:	34/148 - (22%)
Similarity:	58/148 - (39%)	Gaps:	38/148 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 NSSFATP------PFSLSPVGESQGIDRWARVHAFEDVELPLPPVQLVKLPP---------PRQL 338
            :||.|.|      |:...||         ..:.|:|:....:||.:.|..|.         ||.:
Human    25 HSSRALPEMDSRIPYDDYPV---------VFLPAYENPPAWIPPHERVHHPDYNNELTQFLPRTI 80

  Fly   339 VIRRQKSPRQDFGFSLR--KAICLDRTESLTSPIFRPVIFAEPGAGGGATGLLPGDRLIKVNGTP 401
            .::  |.|....||::|  ||..|.        ||...:.  |.:.....||..||:::.||...
Human    81 TLK--KPPGAQLGFNIRGGKASQLG--------IFISKVI--PDSDAHRAGLQEGDQVLAVNDVD 133

  Fly   402 VGELPREIIIEMIRNSGE 419
            ..::.....:|:::.:.|
Human   134 FQDIEHSKAVEILKTARE 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492	19/83 (23%)
		MYSc	556..1317	CDD:214580
		MYSc_Myo18	575..1305	CDD:276837
		GBP_C	<1540..1750	CDD:303769
		COG1340	1565..1833	CDD:224259
		coiled coil	1723..1734	CDD:293879
PDZD11	XP_016885057.1	PDZ_signaling	77..157	CDD:238492	21/87 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900