Protein Alignment Mhcl and Prm

DIOPT Version :10

• Sequence 1: NP_732109.2
• Gene: Mhcl / 41955
• FlyBaseID: FBgn0026059
• Length: 2194
• Species: Drosophila melanogaster
• Sequence 2: NP_523982.2
• Gene: Prm / 39002
• FlyBaseID: FBgn0003149
• Length: 879
• Species: Drosophila melanogaster
• Alignment Length: 904
• Identity: 204/904 - (22%)
• Similarity: 364/904 - (40%)
• Gaps: 197/904 - (21%)

  Fly  1278 DVSVEQILAVNELDVASYRIGPSQILFRSGVLSELEAKRDVLLSDRIIQLQAFCRGYLARKKMSQ 1342
            ||::|.|     .|::|              ||.||.|..:|..|  ::::...|..:.|:|
  Fly    25 DVNIEYI-----QDLSS--------------LSRLEDKIRLLQDD--LEVERELRQRIEREK--- 65

  Fly  1343 RRVQELAVRCIQRNVK----------AFLAVRDWPWWRLLVRVTPLLNVHRTEEQLKTANEE-LL 1396
               .:|:|:.||.:.:          .|.|.|.        |...||.:.:..|.:...:|| .|
  Fly    66 ---ADLSVQVIQMSERLEEAEGGAEHQFEANRK--------RDAELLKLRKLLEDVHLESEETTL 119

  Fly  1397 MLRAKLEKIECD---------RSEVKAEN------------------------------QKLEAK 1422
            :|:.|..:|..|         :::.:||.                              .|||..
  Fly   120 LLKKKHNEIITDFQEQVEILTKNKARAEKDKAKFQTEVYELLSQIESYNKEKIVSEKHISKLEVS 184

  Fly  1423 LSELTVDLAE-ERSTAHIATERLEAETAERLKLEKELGDQTNKVKNLQETTEKLEMELICAKSDL 1486
            :|||.|.:.| .|:...|::.|... :.|.::|.|::.|    :|...:|....:.::|....|.
  Fly   185 ISELNVKIEELNRTVIDISSHRSRL-SQENIELTKDVQD----LKVQLDTVSFSKSQVISQLEDA 244

  Fly  1487 NGISEDEDAENEDGVGGGVYKLKYERVARELEFTKRRLHTQHEHDLEQLVALKKHLEMKLSDA-- 1549
            ....||||...      .:.:....:|..||:..:.:|    |.:.|..:.|::.|....:||
  Fly   245 RRRLEDEDRRR------SLLESSLHQVEIELDSVRNQL----EEESEARIDLERQLVKANADATS 299

  Fly  1550 -----YEEVVEQRQVVGQWKRKAQKMTNEMNDLRMLLEEQNARNNLLEKKQRKFDAECQSLQDAV 1609
                 ..||..:.:.|.:.:||.|....|:.:   .:|....:.|.|||.:.:..:|.:.|...:
  Fly   300 WQNKWNSEVAARAEEVEEIRRKYQVRITELEE---HIESLIVKVNNLEKMKTRLASEVEVLIIDL 361

  Fly  1610 RQERQAKERYGREKDVLQAEKFTLEQTLADT-------RLDLEFKEEKLASLQRELEEMTFGGG- 1666
            .:...:.....:..:.|:.....|:..|.:|       :.||:.|...|.....||:::.....
  Fly   362 EKSNNSCRELTKSVNTLEKHNVELKSRLDETIILYETSQRDLKNKHADLVRTVHELDKVKDNNNQ 426

  Fly  1667 -TEE------EFAQLRRSKNETERRAKEQEEEL-------DEM--------AGQIQLLEQAKLRL 1709
             |.|      :..:.:.:.||..||..|.|.||       ||:        ||: :..||...||
  Fly   427 LTRENKKLGDDLHEAKGAINELNRRLHELELELRRLENERDELTAAYKEAEAGR-KAEEQRGQRL 490

  Fly  1710 EMTLETMRKEARRESQQRDEELEEVRGNGYKKIKALECQ-LETEHEERTLLLREKHELERRLSSM 1773
            .......|.:|.|...::|||:|.:|.....:|:.|..: :|.|...:|.:.|.|.:|:.:::.:
  Fly   491 AADFNQYRHDAERRLAEKDEEIEAIRKQTSIEIEQLNARVIEAETRLKTEVTRIKKKLQIQITEL 555

  Fly  1774 EDRDRVDRDAEEALNQKLRRDLRKYKALLKDAQTQLERLKADTPGKTLIRQLRNQLED-AESARS 1837
            |    :..|.....|..|::.::|....|.:.|...|.::         |||:..|:. |.:.|.
  Fly   556 E----MSLDVANKTNIDLQKVIKKQSLQLTELQAHYEDVQ---------RQLQATLDQYAVAQRR 607

  Fly  1838 LAMKARQTAEAELTEVQAMFDESHRAR-------NDAEERANAAHRDRAELQAQIEENEEELGEL 1895
            ||     ....||.||::..|.::||:       .:|..|.|........|.:...:.|:||..:
  Fly   608 LA-----GLNGELEEVRSHLDSANRAKRTVELQYEEAASRINELTTANVSLVSIKSKLEQELSVV 667

  Fly  1896 MKKYSATVKQLN----------------TEQINVSEAEFKLNEMEAERNNLKEQVAELQHRLDNV 1944
            ...|....|:|.                .||::  |.:.::.::|..:.:|:.:|..|..||:.|
  Fly   668 ASDYEEVSKELRISDERYQKVQVELKHVVEQVH--EEQERIVKLETIKKSLEVEVKNLSIRLEEV 730

  Fly  1945 E-NLGDPSMAMMSKRLELRTKELESRLELEQATRARLE-VQVNRHKEALEK---LQNEVTQSKMR 2004
            | |....|..::|| ||.|.::||  ||||:..|...| :::.|.||...|   :|.|..|..:
  Fly   731 ELNAVAGSKRIISK-LEARIRDLE--LELEEEKRRHAETIKILRKKERTVKEVLVQCEEDQKNL- 791

  Fly  2005 EMQAQDVIKKSQKSLRDMREEFHAVSSREQESLTRRKDLEKKVEQMESEGAALKNDLRL 2063
             :..||.:.||...:...|.:........|::.||.:..::::|..|......::.|.:
  Fly   792 -ILLQDALDKSTAKINIYRRQLSEQEGVSQQTTTRVRRFQRELEAAEDRADTAESSLNI 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mhcl	NP_732109.2	PDZ_canonical	337..426	CDD:483948
		COG5022	541..2019	CDD:227355	197/858 (23%)
		MYSc_Myo18	575..1305	CDD:276837	6/26 (23%)
Prm	NP_523982.2	Myosin_tail_1	<34..853	CDD:460256	199/890 (22%)