DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mhcl and Slc9a3r1

DIOPT Version :9

Sequence 1:	NP_732109.2	Gene:	Mhcl / 41955	FlyBaseID:	FBgn0026059	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	NP_036160.1	Gene:	Slc9a3r1 / 26941	MGIID:	1349482	Length:	355	Species:	Mus musculus

Alignment Length:	221	Identity:	54/221 - (24%)
Similarity:	86/221 - (38%)	Gaps:	55/221 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   333 PPPRQLVIRRQKSPRQDFGFSLRKAICLDRTESLTSPIFRPVIFAEPGAGGGATGLLPGDRLIKV 397
            |.||...:  :|.| ..:||.|         ......:.:.:...|||:....:|||.||||::|
Mouse    10 PLPRLCCL--EKGP-NGYGFHL---------HGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLVEV 62

  Fly   398 NGTPVGELPREIIIEMIRNSGEAV-TVEVQPVA-------------ELV---ELSKRCMAPSTAT 445
            ||..|.:...:.::..||.:..|| .:.|.|..             ||:   |.|::...|:.|.
Mouse    63 NGENVEKETHQQVVSRIRAALNAVRLLVVDPETDERLKKLGVSIREELLRPQEKSEQAEPPAAAD 127

  Fly   446 VEEIDHSITNGNCNTLRRSASKRFKRQSRHENGNGGGEEGGAKGVGHDLEADVADASQPERVWLV 510
            ..|.      |:.|    .|.|...|:.|.....   .:.|..|.|.:|.   :|.|:|
Mouse   128 THEA------GDQN----EAEKSHLRELRPRLCT---MKKGPNGYGFNLH---SDKSKP------ 170

  Fly   511 HRGGFTAAI--RLPTASSGRDEENKL 534
              |.|..|:  ..|..:||...::::
Mouse   171 --GQFIRAVDPDSPAEASGLRAQDRI 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mhcl	NP_732109.2	PDZ_signaling	339..426	CDD:238492	23/87 (26%)
		MYSc	556..1317	CDD:214580
		MYSc_Myo18	575..1305	CDD:276837
		GBP_C	<1540..1750	CDD:303769
		COG1340	1565..1833	CDD:224259
		coiled coil	1723..1734	CDD:293879
Slc9a3r1	NP_036160.1	PDZ_signaling	12..91	CDD:238492	25/90 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	110..146		11/45 (24%)
		PDZ_signaling	147..226	CDD:238492	13/62 (21%)
		EBP50_C	230..355	CDD:286142
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	244..355
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900